HitPredict

Interactor 1: MK13 (O15264)
Mitogen-activated protein kinase 13 (MAP kinase 13) (MAPK 13) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) (Stress-activated protein kinase 4)
Gene: MAPK13

Interactor 2: MBP (P02686)
Myelin basic protein (MBP) (Myelin A1 protein) (Myelin membrane encephalitogenic protein)
Gene: MBP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	17906618
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0032755 - positive regulation of interleukin-6 production
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 365 Hs			1 304
+	Hs
		388075 MK14_HUMAN (1-361): 2.62e-147: 422: 60.22		MBP_HUMAN (1-304): 1.69e-179: 498: 100.00
+	Hs
		388043 MK03_HUMAN (12-354): 6.21e-144: 414: 42.86		MBP_HUMAN (1-304): 1.69e-179: 498: 100.00
+	Hs
		388056 MK12_HUMAN (2-352): 1.88e-143: 412: 65.91		MBP_HUMAN (1-304): 1.69e-179: 498: 100.00
+	Hs
		388073 MK11_HUMAN (1-349): 4.75e-142: 409: 60.57		MBP_HUMAN (1-304): 1.69e-179: 498: 100.00
+	Hs
		388045 MK01_HUMAN (12-355): 8.23e-142: 408: 42.74		MBP_HUMAN (1-304): 1.69e-179: 498: 100.00
+	Hs
		388050 MK08_HUMAN (5-349): 1.77e-109: 328: 46.81		MBP_HUMAN (1-304): 1.69e-179: 498: 100.00
+	Mm
		408244 MK01_MOUSE (12-355): 6.81e-142: 408: 42.74		MBP_MOUSE (1-240): 5.09e-132: 376: 85.06
+	Mm
		408252 MK03_MOUSE (15-354): 4e-141: 407: 43.23		MBP_MOUSE (1-240): 5.09e-132: 376: 85.06
+	Rn
		388098 MK01_RAT (12-355): 6.81e-142: 408: 42.74		MBP_RAT (134-304): 1.79e-87: 261: 81.82
+	Xl
		1018237 Q6DFK6_XENLA (11-351): 1.21e-139: 402: 42.53		MBP_XENLA (134-304): 1.26e-69: 215: 58.01