HitPredict

Interactor 1: HMGB3 (O15347)
High mobility group protein B3 (High mobility group protein 2a) (HMG-2a) (High mobility group protein 4) (HMG-4)
Gene: HMGB3

Interactor 2: MEOX2 (P50222)
Homeobox protein MOX-2 (Growth arrest-specific homeobox) (Mesenchyme homeobox 2)
Gene: MEOX2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	32296183
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 200 Hs			1 304
+	Hs
		186654 HMGB3_HUMAN (13-179): 3.63e-45: 150: 100.00		Q6FHY5_HUMAN (1-304): 9.73e-57: 187: 98.36
+	Hs
		481117 HMGB1_HUMAN (1-171): 2.97e-41: 140: 76.30		HXA10_HUMAN (100-250): 7.8e-37: 137: 33.54
+	Hs
		186628 HMGB3_HUMAN (13-179): 3.63e-45: 150: 100.00		MEOX1_HUMAN (4-270): 1.12e-29: 115: 36.73
+	Hs
		481050 HMGB1_HUMAN (1-171): 2.97e-41: 140: 76.30		HXC6_HUMAN (97-245): 4.56e-33: 123: 32.05
+	Mm
		845553 SOX8_MOUSE (4-92): 6.75e-25: 102: 23.60		HHEX_MOUSE (122-300): 1.15e-36: 133: 23.37
+	Ce
		478991 EGL13_CAEEL (4-119): 7.48e-28: 110: 20.69		MEC3_CAEEL (31-264): 1.39e-32: 124: 20.23
+	Dm
		1014407 Q9VUD3_DROME (2-87): 4.05e-29: 114: 24.42		UBX_DROME (37-248): 1.06e-29: 118: 21.23
+	Dm
		121513 M9PFG6_DROME (7-93): 3.05e-28: 110: 24.14		UBX_DROME (37-248): 1.06e-29: 118: 21.23
+	Dm
		120234 M9PCZ7_DROME (3-84): 8.35e-27: 108: 24.39		UBX_DROME (37-248): 1.06e-29: 118: 21.23
+	Hs
		872735 SOX2_HUMAN (3-94): 1.32e-26: 105: 27.17		ALX4_HUMAN (105-303): 9.69e-29: 115: 23.79
+	Mm
		204336 SOX2_MOUSE (3-94): 3.67e-26: 103: 27.17		ALX4_MOUSE (105-303): 7.57e-29: 115: 22.82
+	Hs
		634834 SOX2_HUMAN (3-94): 1.32e-26: 105: 27.17		HXA5_HUMAN (25-262): 1.54e-28: 112: 24.80
+	Mm
		478349 Q60I23_MOUSE (3-94): 1.85e-26: 104: 27.17		HXA5_MOUSE (25-262): 1.86e-28: 111: 24.02
+	Hs
		481109 HMGB1_HUMAN (1-171): 2.97e-41: 140: 76.30		HXD10_HUMAN (155-245): 2.22e-14: 74.3: 49.45
+	Hs
		634885 SOX17_HUMAN (8-101): 3.57e-22: 94.4: 24.47		HXA5_HUMAN (25-262): 1.54e-28: 112: 24.80
+	Dm
		1014335 Q86BR8_DROME (90-197): 2.96e-11: 62.8: 20.37		UBX_DROME (37-248): 1.06e-29: 118: 21.23
+	Hs
		872079 SOX2_HUMAN (3-94): 1.32e-26: 105: 27.17		MNX1_HUMAN (180-253): 1.38e-14: 75.5: 54.05
+	Mm
		204335 SOX15_MOUSE (7-90): 9.52e-12: 63.6: 28.57		ALX4_MOUSE (105-303): 7.57e-29: 115: 22.82
+	Mm
		1049110 SOX8_MOUSE (4-92): 6.75e-25: 102: 23.60		HXC4_MOUSE (186-244): 1.33e-13: 71.2: 61.02
+	Hs
		239926 SOX15_HUMAN (7-95): 3.29e-12: 64.7: 29.21		MNX1_HUMAN (180-253): 1.38e-14: 75.5: 54.05