HitPredict

Interactor 1: PSDE (O35593)
26S proteasome non-ATPase regulatory subunit 14 (EC 3.4.19.-) (26S proteasome regulatory subunit RPN11) (MAD1)
Gene: Psmd14

Interactor 2: PSB4 (P99026)
Proteasome subunit beta type-4 (Low molecular mass protein 3) (Macropain beta chain) (Multicatalytic endopeptidase complex beta chain) (Proteasome beta chain) (Proteasome chain 3)
Gene: Psmb4

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17139257
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 310 Mm			1 264
+	Hs
		130755 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		PSB4_HUMAN (1-264): 5.54e-87: 261: 93.94
+	Dm
		1358673 PSDE_DROME (1-310): 7.15e-114: 333: 88.39		PSB4_DROME (11-263): 1.85e-78: 239: 39.69
+	Hs
		130644 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		PSA7_HUMAN (31-255): 1.93e-79: 241: 14.47
+	Dm
		1278634 PSDE_DROME (1-310): 7.15e-114: 333: 88.39		PSA5_DROME (26-255): 3.9e-75: 230: 13.82
+	Hs
		130754 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		PSA5_HUMAN (26-252): 3.55e-78: 238: 13.28
+	Dm
		1178949 PSDE_DROME (1-310): 7.15e-114: 333: 88.39		Q7K148_DROME (24-249): 2.92e-73: 227: 24.34
+	Hs
		130747 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		PSA2_HUMAN (28-257): 4.52e-75: 230: 14.71
+	Hs
		130824 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		PSA6_HUMAN (26-261): 1.05e-74: 229: 12.10
+	Dm
		1358675 PSDE_DROME (1-310): 7.15e-114: 333: 88.39		Q9VUJ1_DROME (56-264): 5.17e-71: 220: 16.27
+	Hs
		130757 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		PSB5_HUMAN (16-252): 4.95e-73: 225: 20.68
+	Dm
		771306 PSDE_DROME (1-310): 7.15e-114: 333: 88.39		PSA2_DROME (28-255): 1.98e-69: 215: 14.41
+	Dm
		1358671 PSDE_DROME (1-310): 7.15e-114: 333: 88.39		Q9VJJ0_DROME (55-252): 5.24e-69: 213: 22.11
+	Hs
		131052 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		PSB7_HUMAN (51-253): 1.06e-70: 220: 18.23
+	Hs
		130736 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		PSB1_HUMAN (21-246): 4.14e-67: 209: 22.55
+	Sp
		784769 RPN11_SCHPO (1-309): 7.37e-102: 302: 68.29		PSB2_SCHPO (46-264): 6.53e-73: 225: 18.72
+	Sp
		784779 RPN11_SCHPO (1-309): 7.37e-102: 302: 68.29		PSB7_SCHPO (30-263): 1.12e-72: 224: 40.34
+	Sp
		675389 RPN11_SCHPO (1-309): 7.37e-102: 302: 68.29		PSB5_SCHPO (18-263): 9.52e-70: 217: 21.86
+	Sp
		195130 RPN11_SCHPO (1-309): 7.37e-102: 302: 68.29		PSB1_SCHPO (49-245): 2.49e-63: 199: 18.18
+	Hs
		130798 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		PSB2_HUMAN (56-249): 1.76e-40: 140: 20.51
+	Sp
		784768 RPN11_SCHPO (1-309): 7.37e-102: 302: 68.29		PSB4_SCHPO (55-244): 4.14e-29: 110: 17.71