HitPredict

Interactor 1: STAG2 (O35638)
Cohesin subunit SA-2 (SCC3 homolog 2) (Stromal antigen 2)
Gene: STAG2

Interactor 2: SMC1B (Q920F6)
Structural maintenance of chromosomes protein 1B (SMC protein 1B) (SMC-1-beta) (SMC-1B)
Gene: SMC1B

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	24797474
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000775 - chromosome, centromeric region GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0007062 - sister chromatid cohesion GO:0051321 - meiotic cell cycle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1231 Mm			1 1248
+	Mm
		193223 STAG2_MOUSE (1-1231): 0: 1734: 100.00		SMC1A_MOUSE (1-1222): 3.79e-110: 376: 52.16
+	Hs
		1057313 STAG2_HUMAN (1-1231): 0: 1718: 99.11		SMC1A_HUMAN (1-1222): 5.62e-110: 376: 52.08
+	Xl
		292732 Q5XGV2_XENLA (1-1231): 0: 1664: 85.64		SMC1A_XENLA (1-1222): 7.05e-105: 362: 52.57
+	Mm
		193224 STAG2_MOUSE (1-1231): 0: 1734: 100.00		SMC3_MOUSE (3-1226): 6.48e-72: 265: 15.50
+	Hs
		1232591 STAG2_HUMAN (1-1231): 0: 1718: 99.11		SMC3_HUMAN (3-1226): 8.19e-72: 264: 15.50
+	Xl
		292734 STAG2_XENLA (70-1231): 0: 1619: 88.50		SMC1A_XENLA (1-1222): 7.05e-105: 362: 52.57
+	Mm
		1265314 STAG1_MOUSE (6-1231): 0: 1573: 69.38		SMC1B_MOUSE (1-1248): 3.75e-118: 399: 100.00
+	Hs
		1057335 STAG1_HUMAN (6-1231): 0: 1581: 69.53		SMC1A_HUMAN (1-1222): 5.62e-110: 376: 52.08
+	Xl
		1140122 Q5XGV2_XENLA (1-1231): 0: 1664: 85.64		Q8AW91_XENLA (3-1226): 9.73e-72: 264: 15.34
+	Xl
		292735 STAG1_XENLA (6-1231): 0: 1541: 67.84		SMC1A_XENLA (1-1222): 7.05e-105: 362: 52.57
+	Xl
		292741 STAG2_XENLA (70-1231): 0: 1619: 88.50		SMC3_XENLA (3-1226): 1.92e-72: 266: 15.44
+	Xl
		1206293 STAG2_XENLA (70-1231): 0: 1619: 88.50		Q8AW91_XENLA (3-1226): 9.73e-72: 264: 15.34
+	Hs
		1261592 STAG1_HUMAN (6-1231): 0: 1581: 69.53		SMC3_HUMAN (3-1226): 8.19e-72: 264: 15.50
+	Xl
		292742 STAG1_XENLA (6-1231): 0: 1541: 67.84		SMC3_XENLA (3-1226): 1.92e-72: 266: 15.44
+	Hs
		1057419 STAG3_HUMAN (22-1136): 0: 1307: 51.91		SMC1A_HUMAN (1-1222): 5.62e-110: 376: 52.08
+	Mm
		251066 STAG3_MOUSE (22-1133): 0: 1253: 50.72		SMC1B_MOUSE (1-1248): 3.75e-118: 399: 100.00
+	Hs
		1355962 STAG3_HUMAN (22-1136): 0: 1307: 51.91		SMC3_HUMAN (3-1226): 8.19e-72: 264: 15.50
+	Mm
		251067 STAG3_MOUSE (22-1133): 0: 1253: 50.72		SMC3_MOUSE (3-1226): 6.48e-72: 265: 15.50
+	Dm
		1362841 Q9VM62_DROME (41-1067): 0: 1134: 44.97		Q9VCD8_DROME (2-1221): 5.11e-87: 310: 39.62
+	Sp
		143294 SCC3_SCHPO (41-722): 0: 603: 20.69		SMC3_SCHPO (3-1220): 6.48e-75: 273: 15.21