HitPredict

Interactor 1: EYA1 (O17670)
Protein phosphatase eya-1 (EC 3.1.3.48) (Eyes absent homolog 1)
Gene: eya-1

Interactor 2: Q9N2W3 (Q9N2W3)
Nuclear receptor
Gene: nhr-277

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	23791784
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 503 Ce			1 498
+	Ce
		196280 EYA1_CAEEL (1-503): 0: 520: 100.00		NHR49_CAEEL (65-491): 8.45e-89: 282: 18.69
+	Ce
		112608 EYA1_CAEEL (1-503): 0: 520: 100.00		NH114_CAEEL (56-476): 1.37e-85: 271: 13.55
+	Hs
		1367096 EYA3_HUMAN (3-500): 1.76e-159: 466: 23.30		ESR2_HUMAN (2-497): 4.63e-93: 294: 14.48
+	Ce
		115603 EYA1_CAEEL (1-503): 0: 520: 100.00		H2KZU3_CAEEL (36-468): 2.55e-72: 238: 17.52
+	Ce
		115626 EYA1_CAEEL (1-503): 0: 520: 100.00		H2KZU4_CAEEL (36-468): 2.82e-71: 235: 15.14
+	Ce
		196332 EYA1_CAEEL (1-503): 0: 520: 100.00		Q21372_CAEEL (68-150): 3.32e-13: 73.2: 38.55
+	Hs
		652568 EYA1_HUMAN (26-497): 3.35e-158: 464: 21.97		NR4A1_HUMAN (70-140): 8.59e-13: 72.8: 43.66
+	Hs
		341521 EYA4_HUMAN (25-497): 3.61e-151: 447: 22.67		NR4A1_HUMAN (70-140): 8.59e-13: 72.8: 43.66
+	Hs
		395511 RPB1_HUMAN (60-209): 6.63e-11: 67.3: 15.12		ESR1_HUMAN (2-498): 7.39e-103: 321: 14.51
+	Hs
		1367725 PCLO_HUMAN (3-224): 1.78e-09: 62.7: 11.64		ESR2_HUMAN (2-497): 4.63e-93: 294: 14.48