HitPredict

Interactor 1: A0A0A0MR80 (A0A0A0MR80)
E1A binding protein p400
Gene: EP400

Interactor 2: BRD8 (Q9H0E9)
Bromodomain-containing protein 8 (Skeletal muscle abundant protein) (Skeletal muscle abundant protein 2) (Thyroid hormone receptor coactivating protein of 120 kDa) (TrCP120) (p120)
Gene: BRD8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	unassigned1304
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 985 Hs			1 1235
+	Hs
		1396740 EP400_HUMAN (1-983): 1.69e-117: 400: 99.70		BRD8_HUMAN (1-1235): 0: 590: 100.00
+	Hs
		1256385 E400N_HUMAN (28-505): 2.05e-45: 173: 83.05		BRD8_HUMAN (1-1235): 0: 590: 100.00
+	Mm
		107094 F8VPR5_MOUSE (229-791): 2.83e-38: 158: 16.31		KAT2B_MOUSE (1075-1209): 3.11e-37: 153: 22.96
+	Mm
		312770 SMCA2_MOUSE (449-942): 5.93e-44: 175: 14.51		BRD7_MOUSE (1005-1212): 3.93e-28: 124: 15.49
+	Hs
		1129788 MDC1_HUMAN (28-921): 1.73e-37: 155: 12.65		TRI33_HUMAN (820-1232): 8.49e-34: 143: 11.56
+	Mm
		107090 F8VPR5_MOUSE (229-791): 2.83e-38: 158: 16.31		TRI33_MOUSE (820-1232): 3.78e-32: 138: 11.78
+	Mm
		1231601 SMCA2_MOUSE (449-942): 5.93e-44: 175: 14.51		BAZ1B_MOUSE (555-840): 9.94e-27: 120: 15.73
+	Hs
		1446407 CHD7_HUMAN (170-970): 5.29e-40: 163: 12.86		BRD7_HUMAN (1039-1212): 6.56e-29: 126: 17.32
+	Mm
		74238 F8VPR5_MOUSE (229-791): 2.83e-38: 158: 16.31		EP300_MOUSE (807-1211): 5.16e-30: 131: 15.12
+	Hs
		180887 CBP_HUMAN (225-803): 8.91e-37: 153: 15.27		TIF1A_HUMAN (846-1228): 2.48e-31: 135: 14.11
+	Mm
		107165 SMCA2_MOUSE (449-942): 5.93e-44: 175: 14.51		F8VQD1_MOUSE (1048-1226): 1.96e-22: 107: 16.22
+	Hs
		1288003 CHD7_HUMAN (170-970): 5.29e-40: 163: 12.86		PB1_HUMAN (988-1226): 1.68e-22: 107: 15.51
+	Hs
		903506 CHD7_HUMAN (170-970): 5.29e-40: 163: 12.86		SMCA4_HUMAN (1057-1208): 7.29e-19: 95.5: 13.84
+	Dm
		674041 BRM_DROME (612-983): 5.68e-39: 160: 14.25		Q9VC36_DROME (541-822): 4.63e-18: 92.8: 12.11
+	Hs
		903441 CBP_HUMAN (225-803): 8.91e-37: 153: 15.27		SMCA4_HUMAN (1057-1208): 7.29e-19: 95.5: 13.84
+	Dm
		121973 BRM_DROME (612-983): 5.68e-39: 160: 14.25		M9PH39_DROME (622-802): 6.17e-14: 79.5: 23.28
+	Mm
		107095 F8VPR5_MOUSE (229-791): 2.83e-38: 158: 16.31		KAT2A_MOUSE (684-810): 1.09e-12: 74.9: 17.32
+	Hs
		1129671 MDC1_HUMAN (28-921): 1.73e-37: 155: 12.65		CBP_HUMAN (105-563): 8.91e-10: 65.7: 7.96
+	Hs
		1067330 MDC1_HUMAN (28-921): 1.73e-37: 155: 12.65		EP300_HUMAN (150-707): 9.24e-09: 62.4: 8.45
+	Hs
		1067564 CBP_HUMAN (225-803): 8.91e-37: 153: 15.27		EP300_HUMAN (150-707): 9.24e-09: 62.4: 8.45