Interactor 1: B2L11 (O43521)
Bcl-2-like protein 11 (Bcl2-L-11) (Bcl2-interacting mediator of cell death)
Gene: BCL2L11

Interactor 2: BCL2 (P10415)
Apoptosis regulator Bcl-2
Gene: BCL2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.987

The method score is based on:

Property Details
Experiments 16697956, 17074758, 20836993, 15899854, 9430630, 33961781, 19805519, 17097560, 26186194, 28514442, 15694340, 9731710, 26004684, 17692808, 21671007, 23845444, 21199865, 17289999
Identification Methods unspecified method, affinity chromatography technology, pull down, two hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation, surface plasmon resonance, fluorescence polarization spectroscopy
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Bcl-2~Bclx_interact
Common GO terms GO:0001782 - B cell homeostasis
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005829 - cytosol
GO:0006915 - apoptotic process
and 9 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 198
Hs

1 239
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Last updated: 15 Jul 2024