Interactor 1: NCK2 (O43639)
Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta)
Gene: NCK2

Interactor 2: SRBS1 (Q9BX66)
Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP)
Gene: SORBS1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 11557983
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~SH3_1, SH2~SH3_2, SH3_1~SH3_1, SH3_1~SH3_2, SH3_2~SH3_9, SH3_9~SH3_9
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0030159 - signaling receptor complex adaptor activity
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 380
Hs

1 1292
+ Mm
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+ Rn
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+ Ce
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Last updated: 15 Jul 2024