HitPredict

Interactor 1: PRC1 (O43663)
Protein regulator of cytokinesis 1
Gene: PRC1

Interactor 2: ACTN3 (Q08043)
Alpha-actinin-3 (Alpha-actinin skeletal muscle isoform 3) (F-actin cross-linking protein)
Gene: ACTN3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 620 Hs			1 901
+	Hs
		209626 PRC1_HUMAN (1-620): 2.12e-153: 457: 100.00		ACTN1_HUMAN (19-901): 0: 687: 77.82
+	Hs
		209717 PRC1_HUMAN (1-620): 2.12e-153: 457: 100.00		ACTN2_HUMAN (13-901): 0: 663: 79.98
+	Hs
		209506 PRC1_HUMAN (1-620): 2.12e-153: 457: 100.00		ACTN4_HUMAN (25-901): 0: 651: 74.26
+	Hs
		211632 MY18A_HUMAN (32-595): 2.83e-62: 226: 12.79		ACTN4_HUMAN (25-901): 0: 651: 74.26
+	Hs
		164536 PRC1_HUMAN (1-620): 2.12e-153: 457: 100.00		SPTN2_HUMAN (253-768): 2.12e-12: 73.5: 12.19
+	Hs
		209900 PRC1_HUMAN (1-620): 2.12e-153: 457: 100.00		SPTB2_HUMAN (227-791): 2.62e-11: 70: 10.78
+	Hs
		210273 PRC1_HUMAN (1-620): 2.12e-153: 457: 100.00		SPTN4_HUMAN (215-800): 2.58e-11: 70: 12.86
+	Hs
		209619 PRC1_HUMAN (1-620): 2.12e-153: 457: 100.00		SPTB1_HUMAN (173-841): 8.4e-10: 65: 10.41
+	Hs
		164647 MY18A_HUMAN (32-595): 2.83e-62: 226: 12.79		SPTN2_HUMAN (253-768): 2.12e-12: 73.5: 12.19
+	Hs
		963381 MY18A_HUMAN (32-595): 2.83e-62: 226: 12.79		SPTB2_HUMAN (227-791): 2.62e-11: 70: 10.78
+	Hs
		963335 ITSN1_HUMAN (31-335): 2.15e-15: 82.4: 12.93		SPTB2_HUMAN (227-791): 2.62e-11: 70: 10.78