Interactor 1: ACTN4 (O43707)
Alpha-actinin-4 (Non-muscle alpha-actinin 4)
Gene: ACTN4

Interactor 2: MILK2 (Q8IY33)
MICAL-like protein 2 (Junctional Rab13-binding protein) (Molecule interacting with CasL-like 2) (MICAL-L2)
Gene: MICALL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.61 1.00 0.783

The method score is based on:

Property Details
Experiments 32296183, unassigned1304
Identification Methods two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CH~bMERB_dom, CH~CH, CH~EFhand_Ca_insen, CH~Spectrin
Common GO terms GO:0001725 - stress fiber
GO:0005886 - plasma membrane
GO:0030036 - actin cytoskeleton organization
GO:0051015 - actin filament binding
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 911
Hs

1 904
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024