HitPredict

Interactor 1: WDR62 (O43379)
WD repeat-containing protein 62
Gene: WDR62

Interactor 2: MK08 (P45983)
Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)
Gene: MAPK8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.752

Property	Details
Experiments	19910486, 26186194, 28514442, 33961781, 35271311, 32707033, unassigned3799
Identification Methods	affinity chromatography technology, two hybrid, enzymatic study, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1518 Hs			1 427
+	Hs
		214557 WDR62_HUMAN (1-1518): 0: 829: 100.00		MK10_HUMAN (1-427): 2.45e-164: 472: 90.16
+	Hs
		214552 WDR62_HUMAN (1-1518): 0: 829: 100.00		MK09_HUMAN (1-427): 4.71e-164: 469: 80.80
+	Hs
		853872 FBW1A_HUMAN (364-659): 6.87e-33: 138: 18.18		MK09_HUMAN (1-427): 4.71e-164: 469: 80.80
+	Mm
		1223360 MABP1_MOUSE (2-333): 1.27e-23: 111: 8.31		MK10_MOUSE (1-427): 1.73e-165: 474: 89.46
+	Hs
		246220 MABP1_HUMAN (2-346): 2.51e-22: 107: 9.14		MK08_HUMAN (1-427): 2.77e-165: 472: 100.00
+	Mm
		1237815 MABP1_MOUSE (2-333): 1.27e-23: 111: 8.31		MK09_MOUSE (1-427): 1.1e-161: 463: 81.50
+	Mm
		1237814 MABP1_MOUSE (2-333): 1.27e-23: 111: 8.31		MK08_MOUSE (1-381): 5.08e-153: 440: 99.48
+	Hs
		1153382 FBW1A_HUMAN (364-659): 6.87e-33: 138: 18.18		MK11_HUMAN (4-363): 3.1e-137: 399: 47.11
+	Hs
		667616 LIS1_HUMAN (669-947): 5.65e-32: 132: 8.62		CDK2_HUMAN (23-329): 6.22e-138: 398: 33.23
+	Hs
		1158207 FBW1A_HUMAN (364-659): 6.87e-33: 138: 18.18		MK14_HUMAN (4-365): 1.93e-131: 384: 46.03
+	Hs
		184657 FBW1A_HUMAN (364-659): 6.87e-33: 138: 18.18		MK13_HUMAN (6-373): 9.97e-131: 382: 45.14
+	Hs
		270312 WDR1_HUMAN (2-226): 3.06e-27: 121: 14.49		CDK2_HUMAN (23-329): 6.22e-138: 398: 33.23
+	Hs
		703751 FBW1A_HUMAN (364-659): 6.87e-33: 138: 18.18		MK01_HUMAN (20-359): 2.95e-84: 263: 42.98
+	Hs
		703719 EMAL4_HUMAN (278-927): 2.48e-26: 119: 11.85		MK01_HUMAN (20-359): 2.95e-84: 263: 42.98
+	Hs
		691855 EMAL4_HUMAN (278-927): 2.48e-26: 119: 11.85		MK03_HUMAN (20-359): 5.25e-83: 261: 41.26
+	Hs
		703525 WDR5_HUMAN (566-742): 7.23e-09: 61.2: 23.73		MK01_HUMAN (20-359): 2.95e-84: 263: 42.98