HitPredict

Interactor 1: TLL1 (O43897)
Tolloid-like protein 1 (EC 3.4.24.-)
Gene: TLL1

Interactor 2: BMP1 (P13497)
Bone morphogenetic protein 1 (BMP-1) (EC 3.4.24.19) (Mammalian tolloid protein) (mTld) (Procollagen C-proteinase) (PCP)
Gene: BMP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Astacin~Astacin, CUB~CUB, CUB~EGF_CA, CUB~FXa_inhibition, EGF_CA~FXa_inhibition, FXa_inhibition~FXa_inhibition
Common GO terms GO:0001501 - skeletal system development
GO:0004222 - metalloendopeptidase activity
GO:0004252 - serine-type endopeptidase activity
GO:0005509 - calcium ion binding
GO:0005576 - extracellular region
and 6 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1013
Hs

1 986
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024