HitPredict

Interactor 1: CDK1 (P00546)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (Cell division control protein 28) (Cell division protein kinase 1)
Gene: CDC28

Interactor 2: GIN4 (Q12263)
Serine/threonine-protein kinase GIN4 (EC 2.7.11.1) (Growth inhibitory protein 4)
Gene: GIN4

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.858

The method score is based on:

Property Details
Experiments 14574415, 9544703, 24019491
Identification Methods protein kinase assay, affinity chromatography technology, enzymatic study, protein complementation assay
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
and 2 others

more...
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 298
Sc

1 1142
+ Sc
+ Ca
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024