HitPredict

Interactor 1: AIRE (O43918)
Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein)
Gene: AIRE

Interactor 2: HNRH1 (P31943)
Heterogeneous nuclear ribonucleoprotein H (hnRNP H) [Cleaved into: Heterogeneous nuclear ribonucleoprotein H, N-terminally processed]
Gene: HNRNPH1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	27365398
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PHD~RRM_1
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 545 Hs			1 449
+	Hs
		217429 AIRE_HUMAN (1-545): 1.25e-134: 403: 100.00		PABP1_HUMAN (1-446): 2.77e-84: 272: 13.70
+	Mm
		665773 AIRE_MOUSE (16-544): 2.93e-123: 374: 71.72		PABP1_MOUSE (1-446): 3.46e-84: 272: 13.70
+	Hs
		217461 AIRE_HUMAN (1-545): 1.25e-134: 403: 100.00		HNRPF_HUMAN (253-438): 2.66e-11: 67.3: 26.06
+	Hs
		299039 PHF14_HUMAN (126-484): 3.61e-44: 169: 16.71		HNRH1_HUMAN (1-449): 1.86e-75: 244: 100.00
+	Hs
		1031332 CHD4_HUMAN (74-489): 2.06e-30: 128: 13.43		PABP4_HUMAN (1-447): 8.75e-85: 274: 13.92
+	Hs
		516522 CHD4_HUMAN (74-489): 2.06e-30: 128: 13.43		PABP1_HUMAN (1-446): 2.77e-84: 272: 13.70
+	Hs
		1018458 CHD3_HUMAN (74-503): 9.23e-27: 117: 14.16		PABP4_HUMAN (1-447): 8.75e-85: 274: 13.92
+	Hs
		516483 CHD3_HUMAN (74-503): 9.23e-27: 117: 14.16		PABP1_HUMAN (1-446): 2.77e-84: 272: 13.70
+	Hs
		682815 CHD4_HUMAN (74-489): 2.06e-30: 128: 13.43		HNRH1_HUMAN (1-449): 1.86e-75: 244: 100.00
+	Hs
		682784 CHD3_HUMAN (74-503): 9.23e-27: 117: 14.16		HNRH1_HUMAN (1-449): 1.86e-75: 244: 100.00
+	Hs
		516745 TRI33_HUMAN (336-540): 1.26e-16: 85.6: 16.13		PABP1_HUMAN (1-446): 2.77e-84: 272: 13.70
+	Hs
		201655 SP100_HUMAN (3-296): 1.81e-36: 146: 13.81		MSI1H_HUMAN (5-275): 4.26e-60: 201: 15.39
+	Hs
		1059963 CHD4_HUMAN (74-489): 2.06e-30: 128: 13.43		RBM19_HUMAN (286-371): 5.37e-16: 82.5: 33.72
+	Hs
		855060 CHD4_HUMAN (74-489): 2.06e-30: 128: 13.43		HNRPF_HUMAN (253-438): 2.66e-11: 67.3: 26.06
+	Hs
		682606 CHD4_HUMAN (74-489): 2.06e-30: 128: 13.43		HNRH3_HUMAN (10-86): 1.84e-10: 64.1: 32.47
+	Hs
		582297 CHD4_HUMAN (74-489): 2.06e-30: 128: 13.43		NUCL_HUMAN (75-373): 1.19e-09: 62.5: 18.89
+	Hs
		855034 CHD3_HUMAN (74-503): 9.23e-27: 117: 14.16		HNRPF_HUMAN (253-438): 2.66e-11: 67.3: 26.06
+	Hs
		682590 CHD3_HUMAN (74-503): 9.23e-27: 117: 14.16		HNRH3_HUMAN (10-86): 1.84e-10: 64.1: 32.47
+	Hs
		582257 CHD3_HUMAN (74-503): 9.23e-27: 117: 14.16		NUCL_HUMAN (75-373): 1.19e-09: 62.5: 18.89
+	Hs
		331720 NSD2_HUMAN (30-345): 3.09e-17: 87.5: 14.80		NUCL_HUMAN (75-373): 1.19e-09: 62.5: 18.89