Interactor 1: ORC4 (O43929)
Origin recognition complex subunit 4
Gene: ORC4

Interactor 2: ORC3 (Q9UBD5)
Origin recognition complex subunit 3 (Origin recognition complex subunit Latheo)
Gene: ORC3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 1.00 0.935

The method score is based on:

Property Details
Experiments 10402192, 15910003, 11395502, 11323433, 15232106, 17716973
Identification Methods affinity chromatography technology, biochemical, pull down, protein array, anti bait coimmunoprecipitation
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains AAA_16~ORC3_N, ORC3_N~ORC4_C
Common GO terms GO:0000781 - chromosome, telomeric region
GO:0000808 - origin recognition complex
GO:0003688 - DNA replication origin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 2 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 436
Hs

1 711
+ Hs
+ Hs
+ Dm
+ Dm
+ Dm
+ At
+ At
+ Sp
+ Sp
+ Sp
+ Sc
+ Sc
+ Sc

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Last updated: 15 Jul 2024