HitPredict

Interactor 1: NCK2 (O43639)
Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta)
Gene: NCK2

Interactor 2: TENR (Q92752)
Tenascin-R (TN-R) (Janusin) (Restrictin)
Gene: TNR

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.555

Property	Details
Experiments	25416956
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	SH2~fn3
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 380 Hs			1 1358
+	Hs
		440313 FYN_HUMAN (7-140): 3.47e-22: 99.9: 19.85		PTPRF_HUMAN (524-1257): 8.01e-92: 330: 14.93
+	Mm
		59107 FYN_MOUSE (7-140): 3.37e-22: 99.9: 19.85		PTPRF_MOUSE (524-1268): 5.03e-90: 324: 14.15
+	Hs
		439918 LCK_HUMAN (3-205): 1.6e-19: 91.8: 16.59		PTPRF_HUMAN (524-1257): 8.01e-92: 330: 14.93
+	Hs
		440371 FYN_HUMAN (7-140): 3.47e-22: 99.9: 19.85		PTPRD_HUMAN (415-1086): 5.04e-86: 312: 17.16
+	Hs
		593937 NCK1_HUMAN (1-379): 3.58e-88: 272: 68.24		DCC_HUMAN (778-1261): 2.17e-19: 97.1: 9.65
+	Hs
		50986 NCK2_HUMAN (1-380): 3.54e-95: 290: 100.00		A1L306_HUMAN (2-115): 1.07e-12: 75.1: 8.27
+	Hs
		439950 LCK_HUMAN (3-205): 1.6e-19: 91.8: 16.59		PTPRB_HUMAN (335-1025): 3.64e-58: 223: 17.62
+	Hs
		440539 FYN_HUMAN (7-140): 3.47e-22: 99.9: 19.85		PTPRS_HUMAN (410-1208): 8.11e-55: 213: 13.65
+	Hs
		935712 GRB2_HUMAN (3-60): 5.23e-18: 84: 29.31		MFAP4_HUMAN (1134-1341): 4.46e-57: 200: 46.36
+	Hs
		178668 LYN_HUMAN (2-205): 8.56e-23: 101: 14.56		ANGP2_HUMAN (1136-1342): 2.7e-44: 170: 37.85
+	Hs
		388896 FYN_HUMAN (7-140): 3.47e-22: 99.9: 19.85		FINC_HUMAN (345-862): 4.31e-23: 109: 21.31
+	Hs
		388916 YES_HUMAN (6-137): 1.81e-19: 91.7: 20.15		FINC_HUMAN (345-862): 4.31e-23: 109: 21.31
+	Hs
		463561 LYN_HUMAN (2-205): 8.56e-23: 101: 14.56		SDK2_HUMAN (693-1164): 7.53e-18: 92.5: 9.41
+	Hs
		389258 GRB2_HUMAN (3-60): 5.23e-18: 84: 29.31		FINC_HUMAN (345-862): 4.31e-23: 109: 21.31
+	Hs
		913671 VAV2_HUMAN (3-254): 1.88e-09: 61.3: 11.77		TITIN_HUMAN (527-703): 4.97e-11: 70.1: 12.50