HitPredict

Interactor 1: ACK1 (O54967)
Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2)
Gene: Tnk2

Interactor 2: CLH1 (Q68FD5)
Clathrin heavy chain 1
Gene: Cltc

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	21169560, 17182860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005905 - clathrin-coated pit
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1055 Mm			1 1675
+	Hs
		960761 ACK1_HUMAN (1-1055): 0: 831: 92.89		CLH1_HUMAN (1-1675): 0: 3117: 99.88
+	Hs
		412135 FYN_HUMAN (1-400): 2.25e-129: 405: 30.94		CLH1_HUMAN (1-1675): 0: 3117: 99.88
+	Hs
		522915 SRC_HUMAN (1-400): 1.7e-127: 400: 31.42		CLH1_HUMAN (1-1675): 0: 3117: 99.88
+	Hs
		665391 EPHA3_HUMAN (69-493): 1.79e-116: 384: 26.57		CLH1_HUMAN (1-1675): 0: 3117: 99.88
+	Hs
		960776 TNK1_HUMAN (1-517): 7.11e-120: 384: 40.41		CLH1_HUMAN (1-1675): 0: 3117: 99.88
+	Hs
		338288 EGFR_HUMAN (105-387): 1.28e-52: 203: 38.87		CLH1_HUMAN (1-1675): 0: 3117: 99.88
+	Hs
		338174 EGFR_HUMAN (105-387): 1.28e-52: 203: 38.87		CLH2_HUMAN (1-1634): 0: 2863: 84.95