HitPredict

Interactor 1: MDM35 (O60200)
Mitochondrial distribution and morphology protein 35
Gene: MDM35

Interactor 2: UPS2 (P35200)
Protein UPS2, mitochondrial (Altered inheritance rate of mitochondrion protein 30) (Genetic interactor of prohibitins protein 1) (Unprocessed MGM1 protein 2)
Gene: UPS2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	1.00	0.927

Property	Details
Experiments	27354379, 27241913, 37968396, 20657548, 20622808
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	PRELI~UPF0203
Common GO terms	GO:0005739 - mitochondrion GO:0005758 - mitochondrial intermembrane space GO:0015914 - phospholipid transport GO:1990050 - phosphatidic acid transfer activity
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 86 Sc			1 230
+	Sc
		224237 MDM35_YEAST (1-86): 7.02e-43: 135: 100.00		UPS3_YEAST (1-175): 4.17e-71: 216: 56.57
+	Sc
		224238 MDM35_YEAST (1-86): 7.02e-43: 135: 100.00		UPS1_YEAST (3-172): 2.31e-56: 179: 30.00
+	Hs
		212031 TRIA1_HUMAN (8-62): 4.12e-24: 88.2: 43.64		PLD3B_HUMAN (1-178): 4.3e-70: 214: 32.40
+	Hs
		212022 TRIA1_HUMAN (8-62): 4.12e-24: 88.2: 43.64		PLD3A_HUMAN (1-175): 7.87e-65: 200: 32.96
+	Hs
		212030 TRIA1_HUMAN (8-62): 4.12e-24: 88.2: 43.64		PRLD1_HUMAN (1-173): 2.46e-61: 193: 27.43