HitPredict

Interactor 1: BUB3 (O43684)
Mitotic checkpoint protein BUB3
Gene: BUB3

Interactor 2: NLE1 (Q9NVX2)
Notchless protein homolog 1
Gene: NLE1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 328 Hs			1 485
+	Hs
		1450936 NLE1_HUMAN (86-320): 5.73e-48: 169: 13.03		NLE1_HUMAN (1-485): 4.91e-139: 410: 100.00
+	Hs
		1007752 RAE1L_HUMAN (3-326): 4.38e-81: 252: 33.63		FBXW7_HUMAN (1-310): 1.23e-68: 234: 22.33
+	Hs
		224258 BUB3_HUMAN (1-328): 2.34e-94: 284: 100.00		WDR5_HUMAN (2-231): 2.76e-54: 186: 19.92
+	Hs
		1380064 FBXW7_HUMAN (1-202): 4.67e-46: 167: 20.38		FBXW7_HUMAN (1-310): 1.23e-68: 234: 22.33
+	Mm
		988931 LIS1_MOUSE (1-165): 6.84e-43: 154: 15.71		LIS1_MOUSE (2-275): 5.39e-75: 243: 21.36
+	Hs
		845250 LIS1_HUMAN (1-165): 8.61e-43: 154: 15.71		LIS1_HUMAN (2-275): 7.92e-75: 242: 21.36
+	Hs
		965276 NLE1_HUMAN (86-320): 5.73e-48: 169: 13.03		WDR5_HUMAN (2-231): 2.76e-54: 186: 19.92
+	Hs
		965141 FBXW7_HUMAN (1-202): 4.67e-46: 167: 20.38		WDR5_HUMAN (2-231): 2.76e-54: 186: 19.92
+	Sp
		1068482 TUP11_SCHPO (1-213): 1.77e-63: 213: 17.90		TUP11_SCHPO (1-144): 6.66e-32: 130: 17.31
+	Hs
		845264 LIS1_HUMAN (1-165): 8.61e-43: 154: 15.71		WDR5_HUMAN (2-231): 2.76e-54: 186: 19.92
+	Dm
		1463899 WDS_DROME (1-166): 9.1e-38: 139: 14.61		WDS_DROME (2-235): 1.1e-54: 188: 19.58
+	Hs
		1085692 SNR40_HUMAN (1-122): 1.14e-23: 101: 16.54		TBL3_HUMAN (121-484): 3.93e-59: 210: 19.69
+	Hs
		965151 SNR40_HUMAN (1-122): 1.14e-23: 101: 16.54		WDR5_HUMAN (2-231): 2.76e-54: 186: 19.92
+	Sp
		1068486 TUP11_SCHPO (1-213): 1.77e-63: 213: 17.90		TUP12_SCHPO (106-183): 2.73e-10: 64.7: 37.50
+	Hs
		964797 WDR5_HUMAN (209-320): 1.01e-18: 87: 16.96		WDR5_HUMAN (2-231): 2.76e-54: 186: 19.92
+	Hs
		965071 WDR5B_HUMAN (208-320): 1.09e-18: 87: 16.81		WDR5_HUMAN (2-231): 2.76e-54: 186: 19.92
+	Hs
		1334151 POC1B_HUMAN (134-327): 4.58e-40: 148: 13.73		POC1A_HUMAN (4-85): 2.02e-17: 85.8: 13.42
+	Ca
		515422 TUP1_CANAL (131-320): 2.22e-38: 144: 11.77		TUP1_CANAL (102-306): 1.85e-15: 80.5: 29.95