HitPredict

Interactor 1: CHP2 (O43745)
Calcineurin B homologous protein 2 (Hepatocellular carcinoma-associated antigen 520)
Gene: CHP2

Interactor 2: SL9A2 (Q9UBY0)
Sodium/hydrogen exchanger 2 (Na(+)/H(+) exchanger 2) (NHE-2) (Solute carrier family 9 member 2)
Gene: SLC9A2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.755

Property	Details
Experiments	12576672, unassigned3795
Identification Methods	pull down, anti tag coimmunoprecipitation
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	EF-hand_7~NEXCaM_BD
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 812
+	Rn
		877642 CHP2_RAT (1-196): 2.52e-46: 152: 81.63		SL9A2_RAT (1-812): 0: 813: 90.54
+	Rn
		877641 CHP1_RAT (1-195): 9e-46: 151: 60.51		SL9A2_RAT (1-812): 0: 813: 90.54
+	Hs
		1406244 CHP1_HUMAN (1-195): 5.83e-46: 151: 61.03		SL9A2_HUMAN (1-812): 0: 803: 100.00
+	Hs
		225748 CHP2_HUMAN (1-196): 4.66e-49: 159: 100.00		SL9A4_HUMAN (15-792): 0: 686: 53.68
+	Hs
		1230839 CHP1_HUMAN (1-195): 5.83e-46: 151: 61.03		SL9A4_HUMAN (15-792): 0: 686: 53.68
+	Rn
		686674 CHP2_RAT (1-196): 2.52e-46: 152: 81.63		SL9A4_RAT (41-691): 0: 662: 62.06
+	Rn
		686673 CHP1_RAT (1-195): 9e-46: 151: 60.51		SL9A4_RAT (41-691): 0: 662: 62.06
+	Hs
		225742 CHP2_HUMAN (1-196): 4.66e-49: 159: 100.00		SL9A1_HUMAN (22-801): 0: 624: 45.39
+	Hs
		624666 CHP1_HUMAN (1-195): 5.83e-46: 151: 61.03		SL9A1_HUMAN (22-801): 0: 624: 45.39
+	Hs
		624660 CHP3_HUMAN (12-195): 5.66e-45: 149: 25.85		SL9A1_HUMAN (22-801): 0: 624: 45.39
+	Rn
		686668 CHP2_RAT (1-196): 2.52e-46: 152: 81.63		SL9A1_RAT (22-801): 0: 610: 45.33
+	Rn
		686667 CHP1_RAT (1-195): 9e-46: 151: 60.51		SL9A1_RAT (22-801): 0: 610: 45.33
+	Hs
		225743 CHP2_HUMAN (1-196): 4.66e-49: 159: 100.00		SL9A3_HUMAN (55-791): 0: 575: 40.26
+	Hs
		877712 CHP1_HUMAN (1-195): 5.83e-46: 151: 61.03		SL9A3_HUMAN (55-791): 0: 575: 40.26
+	Rn
		686671 CHP2_RAT (1-196): 2.52e-46: 152: 81.63		SL9A3_RAT (57-791): 0: 562: 39.18
+	Rn
		686670 CHP1_RAT (1-195): 9e-46: 151: 60.51		SL9A3_RAT (57-791): 0: 562: 39.18
+	Hs
		225746 CHP2_HUMAN (1-196): 4.66e-49: 159: 100.00		SL9A5_HUMAN (68-700): 8.74e-175: 528: 43.18
+	Rn
		1283499 CHP2_RAT (1-196): 2.52e-46: 152: 81.63		SL9A5_RAT (44-702): 5.09e-177: 534: 41.99
+	Rn
		956641 CHP1_RAT (1-195): 9e-46: 151: 60.51		SL9A5_RAT (44-702): 5.09e-177: 534: 41.99
+	Hs
		1133802 CHP1_HUMAN (1-195): 5.83e-46: 151: 61.03		SL9A5_HUMAN (68-700): 8.74e-175: 528: 43.18