HitPredict

Interactor 1: SOX15 (O60248)
Transcription factor SOX-15 (Protein SOX-12) (Protein SOX-20) (SRY-box transcription factor 15)
Gene: SOX15

Interactor 2: SRRM2 (Q9UQ35)
Serine/arginine repetitive matrix protein 2 (300 kDa nuclear matrix antigen) (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (SR-related nuclear matrix protein of 300 kDa) (Ser/Arg-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (Tax-responsive enhancer element-binding protein 803) (TaxREB803)
Gene: SRRM2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35140242
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 233 Hs			1 2752
+	Hs
		225775 SOX15_HUMAN (1-233): 8.57e-47: 156: 100.00		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		807628 SOX2_HUMAN (11-229): 9.17e-35: 127: 38.46		MAP1B_HUMAN (15-1517): 8.71e-69: 261: 10.13
+	Hs
		881826 SOX10_HUMAN (43-142): 2.82e-37: 137: 51.49		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		818837 SOX9_HUMAN (38-179): 3.1e-36: 135: 40.14		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		727788 SOX5_HUMAN (21-132): 3.84e-35: 133: 41.07		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		818122 SOX2_HUMAN (11-229): 9.17e-35: 127: 38.46		PRC2B_HUMAN (640-2750): 5.74e-64: 245: 9.36
+	Hs
		818373 SOX2_HUMAN (11-229): 9.17e-35: 127: 38.46		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		817913 SOX2_HUMAN (11-229): 9.17e-35: 127: 38.46		MAP1A_HUMAN (170-2540): 2.1e-44: 181: 9.15
+	Mm
		101612 Q60I23_MOUSE (11-229): 6.74e-35: 128: 38.91		F8VQL9_MOUSE (52-2427): 1.66e-25: 119: 8.77
+	Hs
		818268 SOX2_HUMAN (11-229): 9.17e-35: 127: 38.46		BD1L1_HUMAN (16-2752): 1.77e-19: 99.2: 9.13
+	Hs
		152562 SOX15_HUMAN (1-233): 8.57e-47: 156: 100.00		KMT2D_HUMAN (10-501): 7.91e-09: 63.9: 11.75
+	Hs
		818155 SOX2_HUMAN (11-229): 9.17e-35: 127: 38.46		NIPBL_HUMAN (333-1474): 1.68e-16: 89.1: 14.39
+	Hs
		727710 SOX5_HUMAN (21-132): 3.84e-35: 133: 41.07		PRC2A_HUMAN (8-1230): 6.75e-14: 80.5: 10.65
+	Hs
		727830 SOX5_HUMAN (21-132): 3.84e-35: 133: 41.07		PRC2C_HUMAN (1360-2752): 9.55e-11: 70.1: 9.11
+	Hs
		152619 SOX10_HUMAN (43-142): 2.82e-37: 137: 51.49		KMT2D_HUMAN (10-501): 7.91e-09: 63.9: 11.75
+	Hs
		818819 SOX9_HUMAN (38-179): 3.1e-36: 135: 40.14		KMT2C_HUMAN (1760-2747): 2.06e-09: 65.9: 9.01
+	Hs
		152611 SOX9_HUMAN (38-179): 3.1e-36: 135: 40.14		KMT2D_HUMAN (10-501): 7.91e-09: 63.9: 11.75
+	Hs
		152602 SOX5_HUMAN (21-132): 3.84e-35: 133: 41.07		KMT2D_HUMAN (10-501): 7.91e-09: 63.9: 11.75
+	Hs
		818266 SOX2_HUMAN (11-229): 9.17e-35: 127: 38.46		KMT2C_HUMAN (1760-2747): 2.06e-09: 65.9: 9.01
+	Hs
		152610 SOX2_HUMAN (11-229): 9.17e-35: 127: 38.46		KMT2D_HUMAN (10-501): 7.91e-09: 63.9: 11.75