Interactor 1: BUB1B (O60566)
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (hBUBR1) (Mitotic checkpoint kinase MAD3L) (Protein SSK1)
Gene: BUB1B

Interactor 2: CDC16 (Q13042)
Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (CDC16 homolog) (CDC16Hs) (Cyclosome subunit 6)
Gene: CDC16

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 0.60 0.744

The method score is based on:

Property Details
Experiments 35271311, 24151075, 33961781, 10477750, 32707033, 20360068, 11030144
Identification Methods affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005680 - anaphase-promoting complex
GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0051301 - cell division
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1050
Hs

1 620
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sp
+ Sc
+ Hs
+ Sp
+ Dm
+ Hs
+ Hs
+ Hs
+ Rn
+ Sp
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024