HitPredict

Interactor 1: TSN1 (O60635)
Tetraspanin-1 (Tspan-1) (Tetraspan NET-1) (Tetraspanin TM4-C)
Gene: TSPAN1

Interactor 2: CD9 (P21926)
CD9 antigen (5H9 antigen) (Cell growth-inhibiting gene 2 protein) (Leukocyte antigen MIC3) (Motility-related protein) (MRP-1) (Tetraspanin-29) (Tspan-29) (p24) (CD antigen CD9)
Gene: CD9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Tetraspanin~Tetraspanin
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 241 Hs			1 228
+	Hs
		602239 TSN5_HUMAN (5-241): 1.21e-60: 193: 22.44		CD9_HUMAN (1-228): 5.13e-61: 192: 100.00
+	Hs
		602271 TSN14_HUMAN (5-241): 9.1e-58: 185: 22.84		CD9_HUMAN (1-228): 5.13e-61: 192: 100.00
+	Hs
		446010 CD63_HUMAN (2-241): 1.5e-55: 179: 24.17		CD9_HUMAN (1-228): 5.13e-61: 192: 100.00
+	Hs
		279368 TSN9_HUMAN (2-240): 1.45e-54: 177: 27.92		CD9_HUMAN (1-228): 5.13e-61: 192: 100.00
+	Hs
		602230 CD151_HUMAN (3-241): 3.85e-54: 176: 24.70		CD9_HUMAN (1-228): 5.13e-61: 192: 100.00
+	Hs
		887767 TSN5_HUMAN (5-241): 1.21e-60: 193: 22.44		CD81_HUMAN (1-225): 2.3e-53: 173: 43.59
+	Hs
		279369 TSN5_HUMAN (5-241): 1.21e-60: 193: 22.44		TSN9_HUMAN (4-224): 3.93e-52: 170: 27.97
+	Hs
		819445 TSN5_HUMAN (5-241): 1.21e-60: 193: 22.44		CD151_HUMAN (3-222): 5.02e-51: 167: 30.08
+	Hs
		887904 TSN14_HUMAN (5-241): 9.1e-58: 185: 22.84		CD81_HUMAN (1-225): 2.3e-53: 173: 43.59
+	Hs
		905534 TSN5_HUMAN (5-241): 1.21e-60: 193: 22.44		TSN14_HUMAN (11-225): 6.56e-49: 162: 24.02
+	Hs
		819462 TSN14_HUMAN (5-241): 9.1e-58: 185: 22.84		CD151_HUMAN (3-222): 5.02e-51: 167: 30.08
+	Hs
		819444 CD151_HUMAN (3-241): 3.85e-54: 176: 24.70		CD81_HUMAN (1-225): 2.3e-53: 173: 43.59
+	Hs
		446012 CD63_HUMAN (2-241): 1.5e-55: 179: 24.17		CD82_HUMAN (4-224): 3.81e-46: 155: 24.23
+	Hs
		653088 CD151_HUMAN (3-241): 3.85e-54: 176: 24.70		CD82_HUMAN (4-224): 3.81e-46: 155: 24.23
+	Hs
		237713 CD63_HUMAN (2-241): 1.5e-55: 179: 24.17		TSN2_HUMAN (3-228): 1.77e-44: 150: 46.46
+	Hs
		237719 CD151_HUMAN (3-241): 3.85e-54: 176: 24.70		TSN2_HUMAN (3-228): 1.77e-44: 150: 46.46
+	Hs
		237778 CD63_HUMAN (2-241): 1.5e-55: 179: 24.17		TSN3_HUMAN (6-226): 2.32e-33: 122: 19.75