HitPredict

Interactor 1: POB1 (O74653)
Protein pob1 (BOI protein homolog)
Gene: POB1

Interactor 2: CDC42 (Q01112)
Cell division control protein 42 homolog (CDC42Sp)
Gene: CDC42

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.865

Property	Details
Experiments	19710424, 21899677, 21401840
Identification Methods	affinity chromatography technology, pull down, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	PH~Ras
Common GO terms	GO:0032153 - cell division site GO:0051285 - cell cortex of cell tip GO:0051286 - cell tip
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 871 Sp			1 192
+	Sc
		580319 BOI2_YEAST (8-847): 7.2e-65: 237: 23.74		CDC42_YEAST (1-192): 4.57e-76: 228: 84.90
+	Sc
		580311 BOB1_YEAST (8-849): 1.94e-63: 233: 20.31		CDC42_YEAST (1-192): 4.57e-76: 228: 84.90
+	Hs
		564587 MICA3_HUMAN (50-701): 5.58e-36: 150: 11.14		RHOQ_HUMAN (4-190): 1.13e-87: 258: 64.74
+	Hs
		925204 ANK2_HUMAN (272-701): 8.09e-38: 156: 14.87		RAC1_HUMAN (1-192): 3.29e-83: 246: 68.23
+	Hs
		925387 MICA3_HUMAN (50-701): 5.58e-36: 150: 11.14		RAC1_HUMAN (1-192): 3.29e-83: 246: 68.23
+	Hs
		1186089 MICA3_HUMAN (50-701): 5.58e-36: 150: 11.14		RHOJ_HUMAN (4-189): 7.92e-81: 241: 61.83
+	Hs
		892450 MICA3_HUMAN (50-701): 5.58e-36: 150: 11.14		RAC3_HUMAN (1-191): 1.99e-76: 228: 67.54
+	Ce
		136793 UNC89_CAEEL (48-471): 3.82e-24: 112: 12.50		RAC1_CAEEL (1-192): 1.18e-81: 241: 66.15
+	Hs
		900771 CNKR1_HUMAN (660-853): 9.85e-27: 118: 17.68		RHOA_HUMAN (5-192): 2.36e-77: 231: 54.26
+	Hs
		925374 DNMBP_HUMAN (9-557): 1.43e-21: 103: 12.98		RAC1_HUMAN (1-192): 3.29e-83: 246: 68.23
+	Hs
		297823 K0754_HUMAN (75-486): 1.77e-20: 100: 11.59		RAC1_HUMAN (1-192): 3.29e-83: 246: 68.23
+	Ce
		104464 UNC89_CAEEL (48-471): 3.82e-24: 112: 12.50		G5EBV3_CAEEL (2-192): 5.18e-77: 230: 57.07
+	Ce
		136794 UNC89_CAEEL (48-471): 3.82e-24: 112: 12.50		CDC42_CAEEL (1-192): 4.95e-75: 225: 79.69
+	Hs
		297812 K0754_HUMAN (75-486): 1.77e-20: 100: 11.59		RAC2_HUMAN (1-192): 1.33e-79: 236: 65.63
+	Hs
		951095 DNMBP_HUMAN (9-557): 1.43e-21: 103: 12.98		RHOG_HUMAN (1-192): 1.47e-77: 231: 58.33
+	Hs
		894149 DNMBP_HUMAN (9-557): 1.43e-21: 103: 12.98		CDC42_HUMAN (1-192): 5.71e-77: 230: 81.25
+	Hs
		297820 K0754_HUMAN (75-486): 1.77e-20: 100: 11.59		RHOA_HUMAN (5-192): 2.36e-77: 231: 54.26
+	Hs
		892443 DNMBP_HUMAN (9-557): 1.43e-21: 103: 12.98		RAC3_HUMAN (1-191): 1.99e-76: 228: 67.54
+	Hs
		297819 K0754_HUMAN (75-486): 1.77e-20: 100: 11.59		RAC3_HUMAN (1-191): 1.99e-76: 228: 67.54
+	Hs
		297809 K0754_HUMAN (75-486): 1.77e-20: 100: 11.59		RHOC_HUMAN (5-192): 3.83e-74: 223: 50.53