HitPredict

Interactor 1: TOM1 (O60784)
Target of Myb1 membrane trafficking protein (Target of Myb protein 1)
Gene: TOM1

Interactor 2: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	1.00	0.971

Property	Details
Experiments	26320582, 31350523, 16199040, 15047686, 28190767, 31494268, 38803224, 16196087, 23314748, 17550899
Identification Methods	x-ray crystallography, pull down, affinity chromatography technology, unspecified method
Interaction Type	association, direct interaction, physical association

Property	Details
Interacting Pfam domains	GAT~ubiquitin, VHS~ubiquitin
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0010008 - endosome membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 492 Hs			1 685
+	Hs
		475949 TM1L2_HUMAN (1-492): 2.32e-147: 432: 61.45		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		272789 TM1L1_HUMAN (7-487): 1.65e-105: 324: 29.66		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		476138 STAM1_HUMAN (1-477): 6.09e-92: 291: 19.27		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		476541 GGA1_HUMAN (12-450): 6.7e-91: 291: 21.37		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		476481 GGA3_HUMAN (12-476): 3.9e-84: 276: 21.28		UBC_HUMAN (1-685): 0: 846: 100.00
+	Bt
		477668 Q58CQ6_BOVIN (12-375): 2.46e-91: 286: 23.06		UBC_BOVIN (1-613): 0: 753: 99.18
+	Mm
		292209 TOM1_MOUSE (1-492): 6e-180: 515: 89.43		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Hs
		241134 TOM1_HUMAN (1-492): 5.19e-178: 510: 100.00		ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69
+	Mm
		476811 TM1L2_MOUSE (1-492): 3.82e-149: 437: 60.86		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	At
		285943 TOL6_ARATH (18-428): 4.69e-84: 274: 23.27		UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63
+	Hs
		924099 STAM1_HUMAN (1-477): 6.09e-92: 291: 19.27		RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00
+	Mm
		476958 TM1L1_MOUSE (7-487): 2.09e-99: 308: 28.72		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Mm
		476756 STAM1_MOUSE (1-477): 1.99e-96: 303: 19.27		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Mm
		476921 GGA1_MOUSE (12-450): 2.27e-90: 290: 21.10		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Rn
		78185 B5DF55_RAT (1-477): 3.17e-91: 289: 19.19		UBC_RAT (1-108): 1.27e-29: 127: 90.74
+	Mm
		476884 GGA3_MOUSE (12-481): 1.92e-85: 279: 19.13		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Rn
		1144280 HGS_RAT (10-478): 1.73e-83: 275: 17.87		UBC_RAT (1-108): 1.27e-29: 127: 90.74
+	Hs
		475230 GGA1_HUMAN (12-450): 6.7e-91: 291: 21.37		UBB_HUMAN (1-77): 7.83e-26: 108: 98.70
+	Mm
		476969 HGS_MOUSE (10-478): 6.28e-80: 266: 17.87		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Hs
		475215 GGA3_HUMAN (12-476): 3.9e-84: 276: 21.28		UBB_HUMAN (1-77): 7.83e-26: 108: 98.70