HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: ACOX1 (Q15067)
Peroxisomal acyl-coenzyme A oxidase 1 (AOX) (EC 1.3.3.6) (Palmitoyl-CoA oxidase) (Peroxisomal fatty acyl-CoA oxidase) (Straight-chain acyl-CoA oxidase) (SCOX) [Cleaved into: Peroxisomal acyl-CoA oxidase 1, A chain; Peroxisomal acyl-CoA oxidase 1, B chain; Peroxisomal acyl-CoA oxidase 1, C chain]
Gene: ACOX1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35509820, 35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0030165 - PDZ domain binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 660
+	At
		265700 UBQ3_ARATH (1-77): 1.82e-30: 121: 31.17		ACOX1_ARATH (5-659): 0: 710: 43.12
+	At
		1168397 UBQ3_ARATH (1-77): 1.82e-30: 121: 31.17		ACO12_ARATH (5-659): 0: 700: 42.66
+	Hs
		242945 PRKN_HUMAN (1-465): 2.85e-136: 402: 100.00		ACAD9_HUMAN (6-594): 4e-132: 404: 15.14
+	Hs
		241087 PRKN_HUMAN (1-465): 2.85e-136: 402: 100.00		ACADV_HUMAN (27-569): 1.28e-124: 385: 18.21
+	Hs
		241005 PRKN_HUMAN (1-465): 2.85e-136: 402: 100.00		ACDSB_HUMAN (19-439): 7.53e-115: 352: 14.95
+	Zm
		24793 A0A1D6IJX7_MAIZE (233-459): 1.23e-26: 116: 22.55		A0A1D6N7A4_MAIZE (3-645): 5.63e-180: 528: 25.45
+	At
		515428 UBQ3_ARATH (1-77): 1.82e-30: 121: 31.17		ACOX3_ARATH (2-640): 8.77e-176: 518: 24.85
+	Hs
		888581 ARI1_HUMAN (163-464): 4.18e-73: 242: 19.67		ACADV_HUMAN (27-569): 1.28e-124: 385: 18.21
+	Hs
		240592 PRKN_HUMAN (1-465): 2.85e-136: 402: 100.00		ACADM_HUMAN (110-439): 4.33e-37: 145: 20.12