Protein: FBXL4
F-box/LRR-repeat protein 4 (F-box and leucine-rich repeat protein 4) (F-box protein FBL4/FBL5)

Gene: FBXL4
Organism: Homo sapiens
Interactions: 102
UniProt ID: Q9UKA2

Gene Ontology (top 5):
GO:0000151 - ubiquitin ligase complex
GO:0000422 - autophagy of mitochondrion
GO:0005758 - mitochondrial intermembrane space
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

929109

SKP1
S-phase kinase-associated protein 1

5

20

Small-scale

0.924

High

1041265

CUL1
Cullin-1

3

20

Small-scale

0.827

High

546906

PPAP
Prostatic acid phosphatase

2

1

High-throughput

0.628

High

707402

S10A3
Protein S100-A3

2

1

High-throughput

0.628

High

1356345

FBXL4
F-box/LRR-repeat protein 4

1

20

Small-scale

0.618

High

1234876

TTC9C
Tetratricopeptide repeat protein 9C

3

6

Small-scale

0.609

High

572476

LEG3
Galectin-3

2

0

High-throughput

0.602

High

793700

CACP
Carnitine O-acetyltransferase

2

0

High-throughput

0.602

High

1028292

SBP1
Methanethiol oxidase

2

0

High-throughput

0.602

High

1356346

PADI3
Protein-arginine deiminase type-3

2

0

High-throughput

0.602

High

1356352

NEUR2
Sialidase-2

2

0

High-throughput

0.602

High

1356350

SGT1
Protein SGT1 homolog

2

11

Small-scale

0.584

High

305043

DUS14
Dual specificity protein phosphatase 14

2

2

High-throughput

0.574

High

648634

CALL3
Calmodulin-like protein 3

2

6

High-throughput

0.574

High

846046

PLCD1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1

2

3

High-throughput

0.574

High

1046019

PKP1
Plakophilin-1

2

1

High-throughput

0.574

High

1048818

TRI29
Tripartite motif-containing protein 29

2

2

High-throughput

0.574

High

1197779

DSG4
Desmoglein-4

2

3

High-throughput

0.574

High

1257264

LRC15
Leucine-rich repeat-containing protein 15

2

20

High-throughput

0.574

High

1355233

SUN2
SUN domain-containing protein 2

2

1

High-throughput

0.574

High

1293072

MYO19
Unconventional myosin-XIX

2

0

Small-scale

0.559

High

840857

DYN2
Dynamin-2

1

1

High-throughput

0.515

High

1046354

EXOS2
Exosome complex component RRP4

1

0

High-throughput

0.513

High

1088496

TRXR1
Thioredoxin reductase 1, cytoplasmic

1

0

High-throughput

0.513

High

1219975

BBS7
Bardet-Biedl syndrome 7 protein

1

0

High-throughput

0.513

High

1132867

ODAD2
Outer dynein arm-docking complex subunit 2

1

4

High-throughput

0.489

High

1356353

PKP3
Plakophilin-3

1

1

High-throughput

0.489

High

225224

BNI3L
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

1

1

Small-scale

0.479

High

256998

KDM4A
Lysine-specific demethylase 4A

1

2

Small-scale

0.479

High

273499

PPM1B
Protein phosphatase 1B

1

1

Small-scale

0.479

High

325452

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

1

High-throughput

0.479

High

380703

K2C1
Keratin, type II cytoskeletal 1

1

1

Small-scale

0.479

High

428491

TBB5
Tubulin beta chain

1

4

Small-scale

0.479

High

432347

HS90A
Heat shock protein HSP 90-alpha

1

12

Small-scale

0.479

High

438605

HS90B
Heat shock protein HSP 90-beta

1

14

Small-scale

0.479

High

500199

CH60
60 kDa heat shock protein, mitochondrial

1

3

Small-scale

0.479

High

502668

BIP
Endoplasmic reticulum chaperone BiP

1

8

Small-scale

0.479

High

504929

HSP7C
Heat shock cognate 71 kDa protein

1

7

Small-scale

0.479

High

531435

K1C10
Keratin, type I cytoskeletal 10

1

2

Small-scale

0.479

High

681644

DNJA1
DnaJ homolog subfamily A member 1

1

1

Small-scale

0.479

High

685095

STIP1
Stress-induced-phosphoprotein 1

1

2

Small-scale

0.479

High

724151

K1C9
Keratin, type I cytoskeletal 9

1

1

Small-scale

0.479

High

729195

K22E
Keratin, type II cytoskeletal 2 epidermal

1

2

Small-scale

0.479

High

826088

FAS
Fatty acid synthase

1

2

Small-scale

0.479

High

843088

TCPQ
T-complex protein 1 subunit theta

1

4

Small-scale

0.479

High

871824

HSP72
Heat shock-related 70 kDa protein 2

1

7

Small-scale

0.479

High

875415

TERA
Transitional endoplasmic reticulum ATPase

1

2

Small-scale

0.479

High

892102

ACTB
Actin, cytoplasmic 1

1

1

Small-scale

0.479

High

933660

TBA4A
Tubulin alpha-4A chain

1

3

Small-scale

0.479

High

934019

TBB4B
Tubulin beta-4B chain

1

4

Small-scale

0.479

High

943538

TCPB
T-complex protein 1 subunit beta

1

4

Small-scale

0.479

High

1022069

BNIP3
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

1

1

Small-scale

0.479

High

1053249

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

4

High-throughput

0.479

High

1067855

PDIA6
Protein disulfide-isomerase A6

1

1

Small-scale

0.479

High

1069665

STK38
Serine/threonine-protein kinase 38

1

3

Small-scale

0.479

High

1220784

SIR2
NAD-dependent protein deacetylase sirtuin-2

1

4

High-throughput

0.479

High

1268974

AKAP1
A-kinase anchor protein 1, mitochondrial

1

1

High-throughput

0.479

High

163445

XPO1
Exportin-1

1

0

High-throughput

0.458

High

538055

KPYM
Pyruvate kinase PKM

1

0

Small-scale

0.458

High

598366

FLNA
Filamin-A

1

0

Small-scale

0.458

High

686207

GLPK
Glycerol kinase

1

0

High-throughput

0.458

High

855757

KIF11
Kinesin-like protein KIF11

1

0

Small-scale

0.458

High

1088696

MIC60
MICOS complex subunit MIC60

1

0

Small-scale

0.458

High

1190124

MAVS
Mitochondrial antiviral-signaling protein

1

0

High-throughput

0.458

High

1344340

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.458

High

1356351

FIS1
Mitochondrial fission 1 protein

1

0

High-throughput

0.458

High

161166

CLGN
Calmegin

1

1

Small-scale

0.437

High

297112

TOM70
Mitochondrial import receptor subunit TOM70

1

3

Small-scale

0.437

High

601401

VDAC1
Voltage-dependent anion-selective channel protein 1

1

4

Small-scale

0.437

High

654887

CALX
Calnexin

1

1

Small-scale

0.437

High

671954

PDIA3
Protein disulfide-isomerase A3

1

1

Small-scale

0.437

High

751876

GRP75
Stress-70 protein, mitochondrial

1

9

Small-scale

0.437

High

933390

TBA1B
Tubulin alpha-1B chain

1

3

Small-scale

0.437

High

1037433

TBB3
Tubulin beta-3 chain

1

4

Small-scale

0.437

High

1046615

TBB2A
Tubulin beta-2A chain

1

4

Small-scale

0.437

High

1164388

POTEE
POTE ankyrin domain family member E

1

2

High-throughput

0.437

High

1349239

MTCH1
Mitochondrial carrier homolog 1

1

1

High-throughput

0.437

High

1356348

VDAC3
Voltage-dependent anion-selective channel protein 3

1

4

Small-scale

0.437

High

1356355

MTCH2
Mitochondrial carrier homolog 2

1

1

High-throughput

0.437

High

60705

ODAD3
Outer dynein arm-docking complex subunit 3

3

0

High-throughput

0.347

High

738819

SPB5
Serpin B5

2

0

High-throughput

0.328

High

994027

TGM3
Protein-glutamine gamma-glutamyltransferase E

2

0

High-throughput

0.328

High

1060435

GPNMB
Transmembrane glycoprotein NMB

2

0

High-throughput

0.328

High

1128589

CAHM4
Calcium homeostasis modulator protein 4

2

0

High-throughput

0.328

High

1146479

ATG9B
Autophagy-related protein 9B

2

0

High-throughput

0.328

High

1154399

HPHL1
Ferroxidase HEPHL1

2

0

High-throughput

0.328

High

1197716

LYG2
Lysozyme g-like protein 2

2

0

High-throughput

0.328

High

1271926

DNSL2
Deoxyribonuclease-1-like 2

2

0

High-throughput

0.328

High

1356349

CNPY2
Protein canopy homolog 2

2

0

High-throughput

0.328

High

1356354

CRBG1
Beta/gamma crystallin domain-containing protein 1

2

0

High-throughput

0.328

High

1331102

TRABD
TraB domain-containing protein

2

0

Small-scale

0.305

High

484344

VSIG8
V-set and immunoglobulin domain-containing protein 8

2

0

High-throughput

0.288

High

1158218

MBOA5
Lysophospholipid acyltransferase 5

1

0

High-throughput

0.279

Low

1356347

EPCR
Endothelial protein C receptor

1

0

High-throughput

0.279

Low

154644

TPP1
Tripeptidyl-peptidase 1

1

0

High-throughput

0.268

Low

679515

CPSM
Carbamoyl-phosphate synthase [ammonia], mitochondrial

1

0

Small-scale

0.249

Low

1220704

MIRO2
Mitochondrial Rho GTPase 2

1

0

High-throughput

0.249

Low

1283978

S2546
Mitochondrial outer membrane protein SLC25A46

1

0

High-throughput

0.249

Low

1287220

FAF2
FAS-associated factor 2

1

0

Small-scale

0.249

Low

1288843

ERLEC
Endoplasmic reticulum lectin 1

1

0

Small-scale

0.249

Low

1347728

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024