HitPredict

Interactor 1: DNJA2 (O60884)
DnaJ homolog subfamily A member 2 (Cell cycle progression restoration gene 3 protein) (Dnj3) (Dj3) (HIRA-interacting protein 4) (Renal carcinoma antigen NY-REN-14)
Gene: DNAJA2

Interactor 2: NTRK3 (Q16288)
NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)
Gene: NTRK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0008284 - positive regulation of cell population proliferation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 412 Hs			1 839
+	Hs
		681463 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		NTRK3_HUMAN (1-839): 0: 671: 100.00
+	Hs
		243251 DNJA2_HUMAN (1-412): 1.22e-168: 480: 100.00		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		243277 DNJA2_HUMAN (1-412): 1.22e-168: 480: 100.00		FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43
+	Hs
		384352 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		243293 DNJA2_HUMAN (1-412): 1.22e-168: 480: 100.00		FGFR4_HUMAN (166-837): 6.43e-152: 466: 24.57
+	Hs
		507875 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43
+	Hs
		385330 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		609471 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		FGFR3_HUMAN (140-838): 3.83e-170: 514: 23.73
+	Hs
		508145 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43
+	Hs
		243261 DNJA2_HUMAN (1-412): 1.22e-168: 480: 100.00		RET_HUMAN (282-837): 1.5e-108: 360: 25.76
+	Hs
		608081 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		FGFR4_HUMAN (166-837): 6.43e-152: 466: 24.57
+	Hs
		243254 DNJA2_HUMAN (1-412): 1.22e-168: 480: 100.00		INSR_HUMAN (513-824): 1.34e-64: 238: 39.43
+	Hs
		243262 DNJA2_HUMAN (1-412): 1.22e-168: 480: 100.00		IGF1R_HUMAN (513-820): 3.56e-64: 236: 39.16
+	Hs
		243669 DNJA2_HUMAN (1-412): 1.22e-168: 480: 100.00		ALK_HUMAN (513-816): 2.78e-59: 222: 39.03
+	Hs
		681409 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		ROR2_HUMAN (522-828): 2.97e-67: 243: 41.56
+	Hs
		411313 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		INSR_HUMAN (513-824): 1.34e-64: 238: 39.43
+	Hs
		435551 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		IGF1R_HUMAN (513-820): 3.56e-64: 236: 39.16
+	Hs
		411469 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		INSR_HUMAN (513-824): 1.34e-64: 238: 39.43
+	Hs
		435729 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		IGF1R_HUMAN (513-820): 3.56e-64: 236: 39.16
+	Mm
		1142038 DNJA3_MOUSE (2-395): 4.22e-117: 351: 25.98		MUSK_MOUSE (209-387): 8.99e-22: 103: 25.14