HitPredict

Interactor 1: KIF1B (O60333)
Kinesin-like protein KIF1B (Klp) (EC 5.6.1.3)
Gene: KIF1B

Interactor 2: DLG1 (Q12959)
Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg)
Gene: DLG1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	1.00	0.836

Property	Details
Experiments	29395067, 24550280, 12097473
Identification Methods	proximity labelling technology, phage display, two hybrid, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Guanylate_kin~KIF1B, PH~SH3_1
Common GO terms	GO:0005737 - cytoplasm GO:0005874 - microtubule GO:0043005 - neuron projection
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1816 Hs			1 904
+	Rn
		312761 KIF1B_RAT (1-1816): 0: 1810: 96.81		DLG1_RAT (1-904): 0: 679: 92.65
+	Hs
		246076 KIF1B_HUMAN (1-1816): 0: 1840: 100.00		DLG3_HUMAN (137-904): 0: 569: 66.11
+	Hs
		245914 KIF1B_HUMAN (1-1816): 0: 1840: 100.00		DLG4_HUMAN (175-904): 0: 550: 71.31
+	Rn
		312759 KIF1B_RAT (1-1816): 0: 1810: 96.81		DLG4_RAT (175-904): 0: 549: 71.18
+	Hs
		168597 KIF1B_HUMAN (1-1816): 0: 1840: 100.00		CSKP_HUMAN (19-354): 6.01e-27: 120: 11.36
+	Hs
		245968 KIF1B_HUMAN (1-1816): 0: 1840: 100.00		MPP7_HUMAN (78-319): 5.7e-17: 87.6: 16.87
+	Hs
		1091496 KIF14_HUMAN (1-877): 0: 604: 31.96		DLG1_HUMAN (1-904): 0: 706: 100.00
+	Dm
		56259 A1ZA18_DROME (455-965): 9.31e-101: 362: 25.09		DLG1_DROME (1-904): 2.14e-178: 543: 48.27
+	Hs
		1091574 KI13B_HUMAN (500-1041): 1.78e-16: 88.4: 11.23		DLG1_HUMAN (1-904): 0: 706: 100.00
+	Hs
		1140552 KIF14_HUMAN (1-877): 0: 604: 31.96		PALS1_HUMAN (1-472): 2.58e-18: 92.2: 13.13
+	Hs
		1140394 KIF14_HUMAN (1-877): 0: 604: 31.96		MPP7_HUMAN (78-319): 5.7e-17: 87.6: 16.87
+	Mm
		98001 E9Q4K7_MOUSE (711-1041): 5.04e-17: 90.3: 14.46		DLG4_MOUSE (175-904): 0: 551: 71.31
+	Hs
		1006107 KI13B_HUMAN (500-1041): 1.78e-16: 88.4: 11.23		DLG4_HUMAN (175-904): 0: 550: 71.31
+	Mm
		749850 KIF5A_MOUSE (702-1151): 8.39e-16: 85.7: 9.98		DLG4_MOUSE (175-904): 0: 551: 71.31
+	Mm
		704846 KIF3A_MOUSE (664-892): 4.4e-09: 63.7: 9.44		DLG4_MOUSE (175-904): 0: 551: 71.31
+	Ce
		661899 UN104_CAEEL (4-861): 3.35e-125: 434: 44.24		LIN2_CAEEL (25-395): 8.32e-19: 94.1: 10.32
+	Hs
		168640 KINH_HUMAN (602-1110): 1.03e-23: 111: 9.02		CSKP_HUMAN (19-354): 6.01e-27: 120: 11.36