HitPredict

Interactor 1: PLOD3 (O60568)
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 (EC 1.14.11.4) (Lysyl hydroxylase 3) (LH3); Procollagen glycosyltransferase (EC 2.4.1.50) (EC 2.4.1.66) (Galactosylhydroxylysine-glucosyltransferase) (Procollagen galactosyltransferase) (Procollagen glucosyltransferase)]
Gene: PLOD3

Interactor 2: CO7A1 (Q02388)
Collagen alpha-1(VII) chain (Long-chain collagen) (LC collagen)
Gene: COL7A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0005788 - endoplasmic reticulum lumen
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 738 Hs			1 2944
+	Hs
		251889 PLOD3_HUMAN (1-738): 0: 1341: 100.00		CO4A6_HUMAN (1128-1716): 6.08e-51: 202: 31.64
+	Hs
		251837 PLOD3_HUMAN (1-738): 0: 1341: 100.00		CO4A1_HUMAN (2177-2891): 3.13e-42: 173: 29.78
+	Hs
		251847 PLOD3_HUMAN (1-738): 0: 1341: 100.00		CO4A2_HUMAN (2518-2879): 3.43e-23: 111: 30.77
+	Hs
		251939 PLOD3_HUMAN (1-738): 0: 1341: 100.00		COMA1_HUMAN (38-216): 8.27e-14: 80.5: 41.53
+	Hs
		251957 PLOD3_HUMAN (1-738): 0: 1341: 100.00		COCA1_HUMAN (1865-2064): 8.18e-12: 74: 30.40
+	Hs
		251836 PLOD3_HUMAN (1-738): 0: 1341: 100.00		CO1A1_HUMAN (2584-2784): 3.55e-09: 65.1: 39.22
+	Hs
		1038858 PLOD1_HUMAN (32-738): 0: 1200: 59.38		CO4A6_HUMAN (1128-1716): 6.08e-51: 202: 31.64
+	Hs
		384312 PLOD1_HUMAN (32-738): 0: 1200: 59.38		CO4A1_HUMAN (2177-2891): 3.13e-42: 173: 29.78
+	Hs
		384249 PLOD1_HUMAN (32-738): 0: 1200: 59.38		CO2A1_HUMAN (2183-2782): 3.57e-28: 127: 42.22
+	Hs
		471586 PLOD1_HUMAN (32-738): 0: 1200: 59.38		CO4A2_HUMAN (2518-2879): 3.43e-23: 111: 30.77
+	Hs
		137019 PLOD2_HUMAN (19-738): 0: 1234: 58.75		CO1A1_HUMAN (2584-2784): 3.55e-09: 65.1: 39.22
+	Hs
		920922 PLOD1_HUMAN (32-738): 0: 1200: 59.38		CO4A4_HUMAN (1251-1784): 7.93e-15: 83.6: 36.26
+	Hs
		1038930 PLOD1_HUMAN (32-738): 0: 1200: 59.38		COCA1_HUMAN (1865-2064): 8.18e-12: 74: 30.40
+	Hs
		1038845 PLOD1_HUMAN (32-738): 0: 1200: 59.38		COEA1_HUMAN (776-878): 3.28e-09: 65.1: 23.08
+	Hs
		384138 PLOD1_HUMAN (32-738): 0: 1200: 59.38		CO1A1_HUMAN (2584-2784): 3.55e-09: 65.1: 39.22
+	Dm
		1482039 PLOD_DROME (37-738): 0: 1053: 46.03		Q9VMV5_DROME (2521-2891): 9.43e-29: 129: 28.89
+	Dm
		465904 PLOD_DROME (37-738): 0: 1053: 46.03		CO4A1_DROME (1127-1386): 3.99e-14: 81.3: 22.31
+	Hs
		384317 GT252_HUMAN (283-545): 1.07e-95: 311: 27.89		CO4A1_HUMAN (2177-2891): 3.13e-42: 173: 29.78
+	Hs
		384260 GT252_HUMAN (283-545): 1.07e-95: 311: 27.89		CO2A1_HUMAN (2183-2782): 3.57e-28: 127: 42.22
+	Hs
		384175 GT252_HUMAN (283-545): 1.07e-95: 311: 27.89		CO1A1_HUMAN (2584-2784): 3.55e-09: 65.1: 39.22