HitPredict

Interactor 1: TLR2 (O60603)
Toll-like receptor 2 (Toll/interleukin-1 receptor-like protein 4) (CD antigen CD282)
Gene: TLR2

Interactor 2: MYD88 (Q99836)
Myeloid differentiation primary response protein MyD88
Gene: MYD88

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 0.60 0.743

The method score is based on:

Property Details
Experiments 15107846, 16482509, 17126326, 16893894, 19717524, 20348427, 29990310
Identification Methods two hybrid, anti tag coimmunoprecipitation, affinity chromatography technology, surface plasmon resonance, anti bait coimmunoprecipitation, thermal shift binding
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006915 - apoptotic process
GO:0007165 - signal transduction
and 14 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 784
Hs

1 296
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Service provided by Combinatics, Japan

Last updated: 11Aug2025