HitPredict

Interactor 1: TSN1 (O60635)
Tetraspanin-1 (Tspan-1) (Tetraspan NET-1) (Tetraspanin TM4-C)
Gene: TSPAN1

Interactor 2: CD9 (P21926)
CD9 antigen (5H9 antigen) (Cell growth-inhibiting gene 2 protein) (Leukocyte antigen MIC3) (Motility-related protein) (MRP-1) (Tetraspanin-29) (Tspan-29) (p24) (CD antigen CD9)
Gene: CD9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Tetraspanin~Tetraspanin
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 241 Hs			1 228
+	Hs
		641933 TSN5_HUMAN (5-241): 7.29e-61: 194: 22.84		CD9_HUMAN (1-228): 1.14e-61: 194: 100.00
+	Hs
		641966 TSN14_HUMAN (5-241): 3.94e-57: 184: 23.23		CD9_HUMAN (1-228): 1.14e-61: 194: 100.00
+	Hs
		477403 CD63_HUMAN (2-241): 2.27e-55: 179: 24.17		CD9_HUMAN (1-228): 1.14e-61: 194: 100.00
+	Hs
		298986 TSN9_HUMAN (2-240): 8.96e-55: 177: 27.50		CD9_HUMAN (1-228): 1.14e-61: 194: 100.00
+	Hs
		948746 TSN5_HUMAN (5-241): 7.29e-61: 194: 22.84		CD81_HUMAN (1-225): 3.29e-54: 175: 43.59
+	Hs
		298987 TSN5_HUMAN (5-241): 7.29e-61: 194: 22.84		TSN9_HUMAN (4-224): 2.21e-52: 170: 27.97
+	Hs
		967327 TSN5_HUMAN (5-241): 7.29e-61: 194: 22.84		TSN14_HUMAN (11-225): 2.71e-50: 166: 24.02
+	Hs
		948883 TSN14_HUMAN (5-241): 3.94e-57: 184: 23.23		CD81_HUMAN (1-225): 3.29e-54: 175: 43.59
+	Hs
		873767 TSN5_HUMAN (5-241): 7.29e-61: 194: 22.84		CD151_HUMAN (3-222): 7.64e-50: 164: 30.08
+	Hs
		873784 TSN14_HUMAN (5-241): 3.94e-57: 184: 23.23		CD151_HUMAN (3-222): 7.64e-50: 164: 30.08
+	Hs
		349402 TSN5_HUMAN (5-241): 7.29e-61: 194: 22.84		TSN15_HUMAN (10-222): 6.1e-43: 148: 15.66
+	Hs
		222340 TSN6_HUMAN (4-240): 6.06e-59: 188: 23.21		TSN15_HUMAN (10-222): 6.1e-43: 148: 15.66
+	Hs
		477405 CD63_HUMAN (2-241): 2.27e-55: 179: 24.17		CD82_HUMAN (4-224): 1.08e-46: 157: 24.23
+	Hs
		349494 TSN14_HUMAN (5-241): 3.94e-57: 184: 23.23		TSN15_HUMAN (10-222): 6.1e-43: 148: 15.66
+	Hs
		252580 CD63_HUMAN (2-241): 2.27e-55: 179: 24.17		TSN2_HUMAN (3-228): 5.69e-45: 151: 46.46
+	Hs
		349362 CD63_HUMAN (2-241): 2.27e-55: 179: 24.17		TSN15_HUMAN (10-222): 6.1e-43: 148: 15.66
+	Hs
		298985 TSN9_HUMAN (2-240): 8.96e-55: 177: 27.50		TSN15_HUMAN (10-222): 6.1e-43: 148: 15.66