HitPredict

Interactor 1: IMA7 (O60684)
Importin subunit alpha-7 (Karyopherin subunit alpha-6)
Gene: KPNA6

Interactor 2: NOP58 (Q9Y2X3)
Nucleolar protein 58 (Nucleolar protein 5)
Gene: NOP58

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 536 Hs			1 529
+	Hs
		140678 IMA7_HUMAN (1-536): 4.64e-160: 468: 100.00		NOP56_HUMAN (1-529): 0: 577: 36.75
+	Hs
		911439 IMA5_HUMAN (4-536): 9.82e-147: 434: 80.11		NOP58_HUMAN (1-529): 0: 602: 100.00
+	Hs
		911164 IMA1_HUMAN (1-536): 3.09e-142: 422: 44.92		NOP58_HUMAN (1-529): 0: 602: 100.00
+	Hs
		140658 IMA3_HUMAN (4-536): 4.92e-152: 446: 47.10		NOP56_HUMAN (1-529): 0: 577: 36.75
+	Hs
		140661 IMA6_HUMAN (1-536): 2.47e-149: 440: 83.67		NOP56_HUMAN (1-529): 0: 577: 36.75
+	Hs
		138587 IMA4_HUMAN (4-536): 2.05e-148: 437: 45.98		NOP56_HUMAN (1-529): 0: 577: 36.75
+	Hs
		140821 IMA5_HUMAN (4-536): 9.82e-147: 434: 80.11		NOP56_HUMAN (1-529): 0: 577: 36.75
+	Dm
		1378628 Q9V455_DROME (10-536): 2.59e-140: 416: 44.59		Q95WY3_DROME (1-487): 0: 554: 36.55
+	Sp
		313953 IMA2_SCHPO (11-536): 2.55e-144: 428: 52.26		NOP56_SCHPO (2-441): 0: 538: 38.14
+	Sc
		1039079 IMA1_YEAST (2-536): 3.67e-140: 417: 50.37		NOP56_YEAST (2-430): 2.73e-176: 508: 37.78
+	Sc
		1039084 IMA1_YEAST (2-536): 3.67e-140: 417: 50.37		NOP58_YEAST (2-438): 2.77e-164: 477: 49.55
+	Hs
		911322 IMA5_HUMAN (4-536): 9.82e-147: 434: 80.11		PRP31_HUMAN (154-528): 1.13e-129: 388: 21.83
+	Hs
		911022 IMA1_HUMAN (1-536): 3.09e-142: 422: 44.92		PRP31_HUMAN (154-528): 1.13e-129: 388: 21.83