Interactor 1: ADA23 (O75077)
Disintegrin and metalloproteinase domain-containing protein 23 (ADAM 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3)
Gene: ADAM23

Interactor 2: ADA11 (O75078)
Disintegrin and metalloproteinase domain-containing protein 11 (ADAM 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC)
Gene: ADAM11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ADAM_CR~ADAM_CR, ADAM_CR~Disintegrin, ADAM_CR~Reprolysin, Disintegrin~Disintegrin, Disintegrin~EGF_2, Disintegrin~Reprolysin, Reprolysin~Reprolysin
Common GO terms GO:0004222 - metalloendopeptidase activity
GO:0005178 - integrin binding
GO:0005886 - plasma membrane
GO:0006508 - proteolysis
GO:0008237 - metallopeptidase activity
and 1 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 832
Hs

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Last updated: 15 Jul 2024