Interactor 1: ADA23 (O75077)
Disintegrin and metalloproteinase domain-containing protein 23 (ADAM 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3)
Gene: ADAM23
Interactor 2: ADA11 (O75078)
Disintegrin and metalloproteinase domain-containing protein 11 (ADAM 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC)
Gene: ADAM11
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.47 | 1.00 | 0.691 |
The method score is based on:
Property | Details |
---|---|
Experiments | 33961781 |
Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
Interaction Type | physical association, association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | ADAM_CR~ADAM_CR, ADAM_CR~Disintegrin, ADAM_CR~Reprolysin, Disintegrin~Disintegrin, Disintegrin~EGF_2, Disintegrin~Reprolysin, Reprolysin~Reprolysin |
Common GO terms | GO:0004222 - metalloendopeptidase activity GO:0005178 - integrin binding GO:0005886 - plasma membrane GO:0006508 - proteolysis GO:0008237 - metallopeptidase activity and 1 others more... |
Homologous interactions | 12 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024