HitPredict

Interactor 1: H2B1K (O60814)
Histone H2B type 1-K (H2B K) (HIRA-interacting protein 1)
Gene: H2BC12

Interactor 2: HCLS1 (P14317)
Hematopoietic lineage cell-specific protein (Hematopoietic cell-specific LYN substrate 1) (LckBP1) (p75)
Gene: HCLS1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35575683
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 486
+	Hs
		571673 H2B2F_HUMAN (1-126): 2.2e-54: 168: 97.62		HCLS1_HUMAN (1-486): 1.88e-143: 422: 100.00
+	Hs
		571652 H2B1O_HUMAN (1-126): 2.89e-54: 167: 97.62		HCLS1_HUMAN (1-486): 1.88e-143: 422: 100.00
+	Hs
		449672 H2B1J_HUMAN (1-126): 6.15e-54: 166: 99.21		HCLS1_HUMAN (1-486): 1.88e-143: 422: 100.00
+	Hs
		571662 H2BFS_HUMAN (1-126): 9.85e-54: 166: 98.41		HCLS1_HUMAN (1-486): 1.88e-143: 422: 100.00
+	Hs
		571672 H2B2E_HUMAN (1-126): 5.57e-54: 166: 98.41		HCLS1_HUMAN (1-486): 1.88e-143: 422: 100.00
+	Hs
		571684 H2B1H_HUMAN (1-126): 5.45e-54: 166: 98.41		HCLS1_HUMAN (1-486): 1.88e-143: 422: 100.00
+	Hs
		571655 H2B1B_HUMAN (1-126): 1.53e-53: 165: 96.83		HCLS1_HUMAN (1-486): 1.88e-143: 422: 100.00
+	Hs
		571687 H2B1N_HUMAN (1-126): 2.98e-53: 165: 98.41		HCLS1_HUMAN (1-486): 1.88e-143: 422: 100.00
+	Hs
		571664 H2B1D_HUMAN (1-126): 3.18e-53: 164: 98.41		HCLS1_HUMAN (1-486): 1.88e-143: 422: 100.00
+	Hs
		946775 H2B1D_HUMAN (1-126): 3.18e-53: 164: 98.41		SRC8_HUMAN (1-486): 1.09e-127: 383: 39.86
+	Hs
		386455 H2BFS_HUMAN (1-126): 9.85e-54: 166: 98.41		SPTA1_HUMAN (32-485): 6.82e-59: 212: 15.34
+	Hs
		1117435 H2B1H_HUMAN (1-126): 5.45e-54: 166: 98.41		SPTN1_HUMAN (32-486): 2.51e-44: 169: 14.41
+	Hs
		754836 H2B1B_HUMAN (1-126): 1.53e-53: 165: 96.83		SPTN1_HUMAN (32-486): 2.51e-44: 169: 14.41
+	Hs
		256768 H2B1K_HUMAN (1-126): 1.2e-53: 166: 100.00		NEBU_HUMAN (145-485): 2.78e-35: 142: 16.03
+	Hs
		635512 H2B1C_HUMAN (1-126): 1.08e-53: 166: 99.21		NEBU_HUMAN (145-485): 2.78e-35: 142: 16.03
+	Hs
		635529 H2B2E_HUMAN (1-126): 5.57e-54: 166: 98.41		NEBU_HUMAN (145-485): 2.78e-35: 142: 16.03
+	Hs
		635546 H2B1H_HUMAN (1-126): 5.45e-54: 166: 98.41		NEBU_HUMAN (145-485): 2.78e-35: 142: 16.03
+	Hs
		1091679 H2B2F_HUMAN (1-126): 2.2e-54: 168: 97.62		MYO1E_HUMAN (217-485): 1.77e-34: 139: 18.22
+	Hs
		946764 H2B1D_HUMAN (1-126): 3.18e-53: 164: 98.41		MYO1E_HUMAN (217-485): 1.77e-34: 139: 18.22
+	Hs
		302158 H2B1D_HUMAN (1-126): 3.18e-53: 164: 98.41		NEBL_HUMAN (126-485): 9.9e-34: 137: 13.73