HitPredict

Interactor 1: KDM4A (O75164)
Lysine-specific demethylase 4A (EC 1.14.11.66) (EC 1.14.11.69) (JmjC domain-containing histone demethylation protein 3A) (Jumonji domain-containing protein 2A) ([histone H3]-trimethyl-L-lysine(36) demethylase 4A) ([histone H3]-trimethyl-L-lysine(9) demethylase 4A)
Gene: KDM4A

Interactor 2: H4 (P62805)
Histone H4
Gene: H4C1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.671

Property	Details
Experiments	17190600, 22373579, 16415788
Identification Methods	unspecified method, pull down, isothermal titration calorimetry, surface plasmon resonance, far western blotting
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1064 Hs			1 103
+	Hs
		301132 KDM4B_HUMAN (1-1064): 0: 1049: 49.95		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Sc
		356490 RPH1_YEAST (1-731): 5.06e-148: 463: 22.03		H4_YEAST (18-103): 6.13e-41: 132: 90.70
+	Hs
		876684 BRPF1_HUMAN (432-926): 5.25e-85: 301: 18.70		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Sc
		356687 GIS1_YEAST (4-312): 1.59e-87: 303: 27.94		H4_YEAST (18-103): 6.13e-41: 132: 90.70
+	Hs
		917675 JADE3_HUMAN (715-930): 1.17e-73: 262: 28.51		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		666520 KDM5A_HUMAN (10-56): 1.12e-13: 78.1: 34.04		H4_HUMAN (1-103): 1.38e-48: 151: 100.00