HitPredict

Interactor 1: TRI13 (O60858)
E3 ubiquitin-protein ligase TRIM13 (EC 2.3.2.27) (B-cell chronic lymphocytic leukemia tumor suppressor Leu5) (Leukemia-associated protein 5) (Putative tumor suppressor RFP2) (RING finger protein 77) (RING-type E3 ubiquitin transferase TRIM13) (Ret finger protein 2) (Tripartite motif-containing protein 13)
Gene: TRIM13

Interactor 2: UBE2K (P61086)
Ubiquitin-conjugating enzyme E2 K (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme K) (Huntingtin-interacting protein 2) (HIP-2) (Ubiquitin carrier protein) (Ubiquitin-conjugating enzyme E2-25 kDa) (Ubiquitin-conjugating enzyme E2(25K)) (Ubiquitin-conjugating enzyme E2-25K) (Ubiquitin-protein ligase)
Gene: UBE2K

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	37205848
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_UBOX
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 407 Hs			1 200
+	Hs
		258270 TRI13_HUMAN (1-407): 1.13e-132: 388: 100.00		UB2D2_HUMAN (4-154): 3.47e-75: 224: 41.06
+	Hs
		258263 TRI13_HUMAN (1-407): 1.13e-132: 388: 100.00		UB2D3_HUMAN (4-154): 5.66e-74: 221: 39.74
+	Hs
		258256 TRI13_HUMAN (1-407): 1.13e-132: 388: 100.00		UB2E1_HUMAN (3-153): 1.14e-66: 204: 39.74
+	Hs
		258265 TRI13_HUMAN (1-407): 1.13e-132: 388: 100.00		UBE2N_HUMAN (27-153): 1.06e-37: 129: 51.97
+	Hs
		957675 TRI39_HUMAN (1-315): 2.27e-67: 224: 17.10		UBE2K_HUMAN (1-200): 9.79e-83: 245: 100.00
+	Hs
		623204 RO52_HUMAN (1-321): 2.81e-71: 233: 15.74		UB2D1_HUMAN (4-154): 7.02e-76: 226: 39.74
+	Hs
		623249 RO52_HUMAN (1-321): 2.81e-71: 233: 15.74		UB2D2_HUMAN (4-154): 3.47e-75: 224: 41.06
+	Hs
		623219 RO52_HUMAN (1-321): 2.81e-71: 233: 15.74		UB2D3_HUMAN (4-154): 5.66e-74: 221: 39.74
+	Hs
		906790 TRI39_HUMAN (1-315): 2.27e-67: 224: 17.10		UB2D1_HUMAN (4-154): 7.02e-76: 226: 39.74
+	Mm
		982385 TRI17_MOUSE (2-314): 3.58e-68: 225: 18.10		UB2D2_MOUSE (4-154): 3.47e-75: 224: 41.06
+	Hs
		982330 TRI39_HUMAN (1-315): 2.27e-67: 224: 17.10		UB2D2_HUMAN (4-154): 3.47e-75: 224: 41.06
+	Hs
		957138 TRI58_HUMAN (2-319): 3.88e-68: 225: 16.61		UB2D3_HUMAN (4-154): 5.66e-74: 221: 39.74
+	Mm
		957264 TRI17_MOUSE (2-314): 3.58e-68: 225: 18.10		UB2D3_MOUSE (4-154): 5.66e-74: 221: 39.74
+	Hs
		957208 TRI39_HUMAN (1-315): 2.27e-67: 224: 17.10		UB2D3_HUMAN (4-154): 5.66e-74: 221: 39.74
+	Hs
		623207 RO52_HUMAN (1-321): 2.81e-71: 233: 15.74		UB2E1_HUMAN (3-153): 1.14e-66: 204: 39.74
+	Hs
		1381205 TRI39_HUMAN (1-315): 2.27e-67: 224: 17.10		UB2E3_HUMAN (3-153): 4.5e-68: 208: 40.40
+	Hs
		909393 TRI39_HUMAN (1-315): 2.27e-67: 224: 17.10		UB2E1_HUMAN (3-153): 1.14e-66: 204: 39.74
+	Hs
		75539 TRI39_HUMAN (1-315): 2.27e-67: 224: 17.10		B3KSH4_HUMAN (104-200): 1.64e-61: 187: 100.00
+	Hs
		623221 RO52_HUMAN (1-321): 2.81e-71: 233: 15.74		UBE2N_HUMAN (27-153): 1.06e-37: 129: 51.97
+	Hs
		957847 TRI39_HUMAN (1-315): 2.27e-67: 224: 17.10		UBE2N_HUMAN (27-153): 1.06e-37: 129: 51.97