HitPredict

Interactor 1: LIPA2 (O75334)
Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2)
Gene: PPFIA2

Interactor 2: PP2AA (P67775)
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16) (Replication protein C) (RP-C)
Gene: PPP2CA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	18782753
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1257 Hs			1 309
+	Hs
		255241 LIPA3_HUMAN (1-1257): 1.49e-110: 377: 55.59		PP2AA_HUMAN (1-309): 0: 529: 100.00
+	Hs
		255240 LIPA3_HUMAN (1-1257): 1.49e-110: 377: 55.59		PP2AB_HUMAN (1-309): 0: 528: 97.41
+	Hs
		930827 LIPA1_HUMAN (1-1257): 6.82e-109: 372: 62.89		PP2AA_HUMAN (1-309): 0: 529: 100.00
+	Hs
		915178 LIPA1_HUMAN (1-1257): 6.82e-109: 372: 62.89		PP2AB_HUMAN (1-309): 0: 528: 97.41
+	Hs
		890956 LIPA1_HUMAN (1-1257): 6.82e-109: 372: 62.89		PP4C_HUMAN (4-309): 0: 508: 64.82
+	Dm
		114419 M9PCD4_DROME (1-1182): 6.32e-99: 345: 42.56		PP2A_DROME (1-309): 0: 524: 93.85
+	Hs
		724764 MYH9_HUMAN (1-629): 2.88e-25: 116: 12.71		PP2AA_HUMAN (1-309): 0: 529: 100.00
+	Hs
		725131 MYH10_HUMAN (3-517): 9.54e-21: 101: 12.41		PP2AB_HUMAN (1-309): 0: 528: 97.41
+	Hs
		724689 MYH9_HUMAN (1-629): 2.88e-25: 116: 12.71		PP1G_HUMAN (7-306): 0: 505: 45.96
+	Hs
		724746 MYH9_HUMAN (1-629): 2.88e-25: 116: 12.71		PP1A_HUMAN (5-296): 0: 504: 46.51
+	Hs
		906052 MY18A_HUMAN (41-596): 1.41e-23: 110: 16.28		PP1A_HUMAN (5-296): 0: 504: 46.51
+	Hs
		931058 MRCKB_HUMAN (4-315): 1.39e-11: 71.4: 12.65		PP2AA_HUMAN (1-309): 0: 529: 100.00
+	Hs
		930910 LIPB1_HUMAN (253-485): 3.76e-09: 63.2: 14.41		PP2AA_HUMAN (1-309): 0: 529: 100.00