HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: UBP39 (Q53GS9)
Ubiquitin carboxyl-terminal hydrolase 39 (EC 3.4.19.12) (SAD1 homolog) (U4/U6.U5 tri-snRNP-associated 65 kDa protein)
Gene: USP39

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31239290, 32416067
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1362 Hs			1 565
+	Hs
		260265 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		UBP7_HUMAN (10-557): 1.08e-106: 346: 14.56
+	Hs
		260619 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		UBP22_HUMAN (123-560): 3.83e-112: 346: 17.18
+	Hs
		260099 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		U17L2_HUMAN (201-564): 6.2e-92: 293: 21.95
+	Hs
		259584 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		UBP5_HUMAN (13-493): 6e-87: 288: 15.81
+	Hs
		1141157 BRD3_HUMAN (37-737): 8.76e-57: 213: 47.73		UBP39_HUMAN (1-565): 1.51e-162: 476: 100.00
+	Hs
		674192 BRD2_HUMAN (3-737): 5.3e-54: 206: 46.43		UBP39_HUMAN (1-565): 1.51e-162: 476: 100.00
+	Hs
		1199465 BRD7_HUMAN (238-731): 9.86e-30: 129: 10.56		UBP39_HUMAN (1-565): 1.51e-162: 476: 100.00
+	Sc
		893333 GCN5_YEAST (140-462): 2.78e-42: 163: 14.41		UBP8_YEAST (80-553): 2.12e-107: 331: 16.46
+	Hs
		259652 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		UBP11_HUMAN (439-556): 3.91e-09: 61.6: 31.09
+	Hs
		1371713 BRD7_HUMAN (238-731): 9.86e-30: 129: 10.56		UBP7_HUMAN (10-557): 1.08e-106: 346: 14.56
+	Sp
		1439862 YK82_SCHPO (49-215): 1.44e-35: 147: 26.35		UBP71_SCHPO (20-557): 6.21e-97: 320: 14.90
+	Hs
		1369225 KAT2B_HUMAN (327-456): 5.64e-22: 105: 26.92		UBP22_HUMAN (123-560): 3.83e-112: 346: 17.18
+	Sc
		762987 SPT7_YEAST (223-611): 5.84e-25: 115: 12.21		UBP8_YEAST (80-553): 2.12e-107: 331: 16.46
+	Hs
		1258101 KAT2B_HUMAN (327-456): 5.64e-22: 105: 26.92		UBP51_HUMAN (123-559): 8.13e-106: 335: 15.96
+	Dm
		1486388 Q9VTZ1_DROME (336-457): 5.43e-22: 105: 30.89		NOT_DROME (124-560): 7.65e-104: 323: 17.67
+	Dm
		303755 O76216_DROME (336-457): 5.43e-22: 105: 30.89		NOT_DROME (124-560): 7.65e-104: 323: 17.67
+	Sp
		1018067 SPT7_SCHPO (128-628): 4.51e-25: 115: 11.83		UBP8_SCHPO (81-556): 8.14e-96: 301: 17.32
+	Hs
		67139 KAT2B_HUMAN (327-456): 5.64e-22: 105: 26.92		UBP27_HUMAN (190-563): 6.81e-96: 301: 16.83
+	Hs
		342133 BRD1_HUMAN (192-769): 1.38e-30: 133: 13.50		UBP11_HUMAN (439-556): 3.91e-09: 61.6: 31.09
+	Hs
		907590 BRD7_HUMAN (238-731): 9.86e-30: 129: 10.56		UBP11_HUMAN (439-556): 3.91e-09: 61.6: 31.09