HitPredict

Interactor 1: TNAP3 (Q60769)
Tumor necrosis factor alpha-induced protein 3 (TNF alpha-induced protein 3) (EC 2.3.2.-) (EC 3.4.19.12) (Putative DNA-binding protein A20) (Zinc finger protein A20)
Gene: Tnfaip3

Interactor 2: TNIP1 (Q9WUU8)
TNFAIP3-interacting protein 1 (A20-binding inhibitor of NF-kappa-B activation 1) (ABIN) (ABIN-1) (Nef-associated factor 1) (Naf1) (Virion-associated nuclear shuttling protein) (VAN) (mVAN)
Gene: TNIP1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 0.60 0.705

The method score is based on:

Property Details
Experiments 29203883, 19060883, 11389905, 10385526, 12586352
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006954 - inflammatory response
GO:0043124 - negative regulation of canonical NF-kappaB signal transduction
GO:0071222 - cellular response to lipopolysaccharide
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 775
Mm

1 647
+ Hs
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+ Mm
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+ Mm
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Last updated: 15 Jul 2024