HitPredict

Interactor 1: PR40A (O75400)
Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6)
Gene: PRPF40A

Interactor 2: SFPQ (P23246)
Splicing factor, proline- and glutamine-rich (100 kDa DNA-pairing protein) (hPOMp100) (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor)
Gene: SFPQ

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	16055720
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0016363 - nuclear matrix GO:0016607 - nuclear speck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 957 Hs			1 707
+	Hs
		263637 PR40A_HUMAN (1-957): 5.9e-97: 328: 100.00		NONO_HUMAN (265-707): 1.49e-70: 239: 56.98
+	Hs
		263758 PR40A_HUMAN (1-957): 5.9e-97: 328: 100.00		PSPC1_HUMAN (230-707): 1.7e-60: 213: 51.96
+	Mm
		93571 DESP_MOUSE (362-952): 1.3e-61: 231: 13.30		SFPQ_MOUSE (230-707): 1.53e-70: 245: 98.95
+	Hs
		154746 TCRG1_HUMAN (6-820): 7.38e-41: 165: 16.47		SFPQ_HUMAN (1-707): 4.51e-74: 255: 100.00
+	Hs
		613369 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		SFPQ_HUMAN (1-707): 4.51e-74: 255: 100.00
+	Hs
		516402 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		PABP1_HUMAN (287-700): 1.59e-70: 243: 16.46
+	Hs
		154809 TCRG1_HUMAN (6-820): 7.38e-41: 165: 16.47		NONO_HUMAN (265-707): 1.49e-70: 239: 56.98
+	Hs
		808625 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		NONO_HUMAN (265-707): 1.49e-70: 239: 56.98
+	Hs
		808925 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		PABP3_HUMAN (287-700): 9.1e-69: 239: 16.88
+	Hs
		154847 TCRG1_HUMAN (6-820): 7.38e-41: 165: 16.47		PSPC1_HUMAN (230-707): 1.7e-60: 213: 51.96
+	Hs
		269204 WBP4_HUMAN (102-385): 6.66e-27: 115: 14.68		SFPQ_HUMAN (1-707): 4.51e-74: 255: 100.00
+	Hs
		269201 WBP4_HUMAN (102-385): 6.66e-27: 115: 14.68		PABP1_HUMAN (287-700): 1.59e-70: 243: 16.46
+	Hs
		269236 WBP4_HUMAN (102-385): 6.66e-27: 115: 14.68		NONO_HUMAN (265-707): 1.49e-70: 239: 56.98
+	Hs
		516643 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		PABP1_HUMAN (287-700): 1.59e-70: 243: 16.46
+	Hs
		125157 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		SFPQ_HUMAN (1-707): 4.51e-74: 255: 100.00
+	Sc
		376704 PRP40_YEAST (144-667): 4.38e-18: 91.1: 16.90		PABP_YEAST (293-687): 2.32e-69: 239: 15.84
+	Hs
		269259 WBP4_HUMAN (102-385): 6.66e-27: 115: 14.68		PSPC1_HUMAN (230-707): 1.7e-60: 213: 51.96
+	Hs
		1069788 WWP1_HUMAN (22-297): 5.32e-15: 81.7: 13.88		NONO_HUMAN (265-707): 1.49e-70: 239: 56.98
+	Hs
		125122 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		PABP1_HUMAN (287-700): 1.59e-70: 243: 16.46
+	Dm
		113976 M9PB30_DROME (2-350): 4.07e-23: 108: 10.15		M9PB30_DROME (104-275): 2.02e-10: 66.8: 18.78