Interactor 1: CDC45 (O75419)
Cell division control protein 45 homolog (PORC-PI-1)
Gene: CDC45

Interactor 2: MCM5 (P33992)
DNA replication licensing factor MCM5 (EC 3.6.4.12) (CDC46 homolog) (P1-CDC46)
Gene: MCM5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 23364835
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CDC45~MCM_lid, CDC45~MCM_N, CDC45~MCM_OB
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0003688 - DNA replication origin binding
GO:0003697 - single-stranded DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 3 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 566
Hs

1 734
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Dm
+ Dm
+ Sp
+ Sp
+ Sc
+ Sc
+ Sc
+ Sc
+ Sp
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024