HitPredict

Interactor 1: STX11 (O75558)
Syntaxin-11
Gene: STX11

Interactor 2: TBK1 (Q9UHD2)
Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)
Gene: TBK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.610

Property	Details
Experiments	28514442, 33961781, 21988832
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 287 Hs			1 729
+	Hs
		1017840 STX4_HUMAN (1-286): 1.54e-58: 190: 27.53		TBK1_HUMAN (1-729): 0: 564: 100.00
+	Hs
		1030201 STX3_HUMAN (1-276): 4.38e-55: 181: 30.44		TBK1_HUMAN (1-729): 0: 564: 100.00
+	Hs
		1205393 STX12_HUMAN (47-283): 7.51e-44: 152: 19.09		TBK1_HUMAN (1-729): 0: 564: 100.00
+	Hs
		1233516 STX19_HUMAN (1-278): 6.69e-42: 147: 35.92		TBK1_HUMAN (1-729): 0: 564: 100.00
+	Hs
		1017665 STX4_HUMAN (1-286): 1.54e-58: 190: 27.53		MRCKA_HUMAN (6-698): 6.44e-109: 365: 17.31
+	Ce
		248153 STX4_CAEEL (37-278): 1.8e-45: 156: 23.46		KCC2D_CAEEL (3-589): 2.73e-116: 368: 16.67
+	Hs
		178587 STX7_HUMAN (56-275): 1e-44: 154: 15.25		MRCKA_HUMAN (6-698): 6.44e-109: 365: 17.31
+	Hs
		647881 STX4_HUMAN (1-286): 1.54e-58: 190: 27.53		MARK3_HUMAN (9-267): 1.86e-85: 287: 28.08
+	Hs
		178402 STX7_HUMAN (56-275): 1e-44: 154: 15.25		MARK3_HUMAN (9-267): 1.86e-85: 287: 28.08