Protein: RHG25
Rho GTPase-activating protein 25 (Rho-type GTPase-activating protein 25)

Gene: RHG25, ARHGAP25
Organism: Homo sapiens
Interactions: 56
UniProt ID: P42331

Gene Ontology (top 5):
GO:0001891 - phagocytic cup
GO:0005096 - GTPase activator activity
GO:0006911 - phagocytosis, engulfment
GO:0007015 - actin filament organization
GO:0007165 - signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

838929

DMWD
Dystrophia myotonica WD repeat-containing protein

3

4

High-throughput

0.770

High

838930

TBL3
Transducin beta-like protein 3

3

4

High-throughput

0.770

High

838942

DUSTY
Dual serine/threonine and tyrosine protein kinase

3

13

High-throughput

0.770

High

838934

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

3

5

High-throughput

0.731

High

838935

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

3

5

High-throughput

0.731

High

838938

RBBP7
Histone-binding protein RBBP7

2

3

High-throughput

0.659

High

838951

TCAB1
Telomerase Cajal body protein 1

1

5

High-throughput

0.618

High

362916

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.618

High

48344

UBA6
Ubiquitin-like modifier-activating enzyme 6

3

3

High-throughput

0.609

High

193756

PER1
Period circadian protein homolog 1

3

1

High-throughput

0.609

High

315234

RECQ4
ATP-dependent DNA helicase Q4

3

5

High-throughput

0.609

High

334153

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

3

4

High-throughput

0.609

High

833710

KDM5C
Lysine-specific demethylase 5C

3

3

High-throughput

0.609

High

838940

TRI65
E3 ubiquitin-protein ligase TRIM65

2

6

High-throughput

0.558

High

838958

S23IP
SEC23-interacting protein

2

2

High-throughput

0.558

High

838941

POTEE
POTE ankyrin domain family member E

1

19

High-throughput

0.553

High

724723

METK2
S-adenosylmethionine synthase isoform type-2

2

4

High-throughput

0.521

High

838954

MAT2B
Methionine adenosyltransferase 2 subunit beta

2

2

High-throughput

0.521

High

838957

MTCH2
Mitochondrial carrier homolog 2

2

6

High-throughput

0.521

High

187023

PPM1G
Protein phosphatase 1G

1

1

High-throughput

0.479

High

838928

LG3BP
Galectin-3-binding protein

1

5

High-throughput

0.479

High

838948

NEB2
Neurabin-2

1

17

High-throughput

0.479

High

838955

HACD3
Very-long-chain

1

2

High-throughput

0.479

High

821245

TCPZ
T-complex protein 1 subunit zeta

1

4

High-throughput

0.470

High

838923

VDAC2
Non-selective voltage-gated ion channel VDAC2

1

1

High-throughput

0.470

High

838943

CDHR3
Cadherin-related family member 3

1

3

High-throughput

0.470

High

838946

MAGB6
Melanoma-associated antigen B6

1

6

High-throughput

0.470

High

838931

NPRL3
GATOR1 complex protein NPRL3

1

0

High-throughput

0.458

High

155837

DPYL4
Dihydropyrimidinase-related protein 4

1

1

High-throughput

0.437

High

172541

XPO1
Exportin-1

1

16

High-throughput

0.437

High

228456

LANC1
Glutathione S-transferase LANCL1

1

1

High-throughput

0.437

High

316773

MTA2
Metastasis-associated protein MTA2

1

2

High-throughput

0.437

High

571896

TRI27
Zinc finger protein RFP

1

4

High-throughput

0.437

High

647495

UBA1
Ubiquitin-like modifier-activating enzyme 1

1

3

High-throughput

0.437

High

717711

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

5

High-throughput

0.437

High

838921

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

11

High-throughput

0.437

High

838924

P5CS
Delta-1-pyrroline-5-carboxylate synthase

1

3

High-throughput

0.437

High

838925

ITA1
Integrin alpha-1

1

1

High-throughput

0.437

High

838926

IF6
Eukaryotic translation initiation factor 6

1

2

High-throughput

0.437

High

838927

CKAP4
Cytoskeleton-associated protein 4

1

14

High-throughput

0.437

High

838932

ACACA
Acetyl-CoA carboxylase 1

1

3

High-throughput

0.437

High

838933

PRDX4
Peroxiredoxin-4

1

4

High-throughput

0.437

High

838937

HERC3
Probable E3 ubiquitin-protein ligase HERC3

1

9

High-throughput

0.437

High

838944

DPP9
Dipeptidyl peptidase 9

1

4

High-throughput

0.437

High

838922

HD
Huntingtin

1

7

High-throughput

0.417

High

838950

MSTO1
Protein misato homolog 1

3

0

High-throughput

0.347

High

838939

AP5B1
AP-5 complex subunit beta-1

2

0

High-throughput

0.318

High

680806

PSA1
Proteasome subunit alpha type-1

1

0

High-throughput

0.249

Low

702890

DPOD1
DNA polymerase delta catalytic subunit

1

0

High-throughput

0.249

Low

838936

TF2H2
General transcription factor IIH subunit 2

1

0

High-throughput

0.249

Low

838947

DYHC2
Cytoplasmic dynein 2 heavy chain 1

1

0

High-throughput

0.249

Low

838949

INT14
Integrator complex subunit 14

1

0

High-throughput

0.249

Low

838952

THUM3
tRNA

1

0

High-throughput

0.249

Low

838953

WDCP
WD repeat and coiled-coil-containing protein

1

0

High-throughput

0.249

Low

838956

ANGE1
Protein angel homolog 1

1

0

High-throughput

0.249

Low

838945

ARF
Tumor suppressor ARF

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025