HitPredict

Interactor 1: IGSF3 (O75054)
Immunoglobulin superfamily member 3 (IgSF3) (Glu-Trp-Ile EWI motif-containing protein 3) (EWI-3)
Gene: IGSF3

Interactor 2: TSN5 (P62079)
Tetraspanin-5 (Tspan-5) (Tetraspan NET-4) (Transmembrane 4 superfamily member 9)
Gene: TSPAN5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	26686862
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Tetraspanin~V-set
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1194 Hs			1 268
+	Hs
		269877 IGSF3_HUMAN (1-1194): 0: 770: 100.00		TSN14_HUMAN (1-266): 7.39e-86: 258: 58.27
+	Hs
		269820 IGSF3_HUMAN (1-1194): 0: 770: 100.00		TSN15_HUMAN (14-263): 1.85e-62: 199: 34.00
+	Hs
		269835 IGSF3_HUMAN (1-1194): 0: 770: 100.00		CD9_HUMAN (11-265): 1.12e-48: 162: 24.32
+	Hs
		967365 FPRP_HUMAN (284-1109): 1.76e-53: 204: 19.19		TSN5_HUMAN (1-268): 6.91e-90: 268: 100.00
+	Hs
		1339815 FPRP_HUMAN (284-1109): 1.76e-53: 204: 19.19		TSN14_HUMAN (1-266): 7.39e-86: 258: 58.27
+	Hs
		967334 IGSF8_HUMAN (689-1117): 1.81e-34: 143: 17.31		TSN5_HUMAN (1-268): 6.91e-90: 268: 100.00
+	Hs
		349597 FPRP_HUMAN (284-1109): 1.76e-53: 204: 19.19		TSN15_HUMAN (14-263): 1.85e-62: 199: 34.00
+	Hs
		697368 FPRP_HUMAN (284-1109): 1.76e-53: 204: 19.19		CD82_HUMAN (11-267): 5.21e-61: 195: 28.09
+	Hs
		873796 FPRP_HUMAN (284-1109): 1.76e-53: 204: 19.19		CD151_HUMAN (5-266): 6.5e-57: 184: 22.64
+	Hs
		477478 FPRP_HUMAN (284-1109): 1.76e-53: 204: 19.19		CD63_HUMAN (11-263): 9.67e-57: 183: 24.90
+	Hs
		948953 FPRP_HUMAN (284-1109): 1.76e-53: 204: 19.19		CD81_HUMAN (12-264): 1.1e-50: 167: 22.99
+	Hs
		641987 FPRP_HUMAN (284-1109): 1.76e-53: 204: 19.19		CD9_HUMAN (11-265): 1.12e-48: 162: 24.32
+	Hs
		349521 IGSF8_HUMAN (689-1117): 1.81e-34: 143: 17.31		TSN15_HUMAN (14-263): 1.85e-62: 199: 34.00
+	Hs
		697359 IGSF8_HUMAN (689-1117): 1.81e-34: 143: 17.31		CD82_HUMAN (11-267): 5.21e-61: 195: 28.09
+	Hs
		948902 IGSF8_HUMAN (689-1117): 1.81e-34: 143: 17.31		CD81_HUMAN (12-264): 1.1e-50: 167: 22.99
+	Hs
		641970 IGSF8_HUMAN (689-1117): 1.81e-34: 143: 17.31		CD9_HUMAN (11-265): 1.12e-48: 162: 24.32
+	Hs
		349432 SDK2_HUMAN (737-1194): 3.97e-20: 99.6: 12.45		TSN15_HUMAN (14-263): 1.85e-62: 199: 34.00
+	Mm
		776905 IGSF8_MOUSE (11-432): 1.33e-29: 128: 16.45		CD81_MOUSE (12-264): 1.46e-49: 164: 22.61
+	Hs
		252640 FPRP_HUMAN (284-1109): 1.76e-53: 204: 19.19		TSN2_HUMAN (14-155): 1.91e-14: 72.4: 34.93
+	Hs
		252619 IGSF8_HUMAN (689-1117): 1.81e-34: 143: 17.31		TSN2_HUMAN (14-155): 1.91e-14: 72.4: 34.93