HitPredict

Interactor 1: TSN2 (O60636)
Tetraspanin-2 (Tspan-2) (Tetraspan NET-3)
Gene: TSPAN2

Interactor 2: IGSF8 (Q969P0)
Immunoglobulin superfamily member 8 (IgSF8) (CD81 partner 3) (Glu-Trp-Ile EWI motif-containing protein 2) (EWI-2) (Keratinocytes-associated transmembrane protein 4) (KCT-4) (LIR-D1) (Prostaglandin regulatory-like protein) (PGRL) (CD antigen CD316)
Gene: IGSF8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Tetraspanin~V-set
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 221 Hs			1 613
+	Hs
		641970 CD9_HUMAN (4-221): 6.57e-52: 169: 46.02		IGSF8_HUMAN (1-613): 8.33e-173: 506: 100.00
+	Hs
		948902 CD81_HUMAN (4-217): 9.18e-49: 161: 40.69		IGSF8_HUMAN (1-613): 8.33e-173: 506: 100.00
+	Hs
		967334 TSN5_HUMAN (8-218): 2.45e-48: 161: 23.44		IGSF8_HUMAN (1-613): 8.33e-173: 506: 100.00
+	Mm
		776905 CD81_MOUSE (4-217): 1.05e-46: 155: 40.69		IGSF8_MOUSE (22-613): 2.13e-171: 502: 90.20
+	Hs
		697359 CD82_HUMAN (5-217): 6.36e-42: 144: 22.87		IGSF8_HUMAN (1-613): 8.33e-173: 506: 100.00
+	Hs
		252640 TSN2_HUMAN (1-221): 1.58e-52: 170: 100.00		FPRP_HUMAN (37-604): 5.77e-51: 191: 19.90
+	Hs
		641987 CD9_HUMAN (4-221): 6.57e-52: 169: 46.02		FPRP_HUMAN (37-604): 5.77e-51: 191: 19.90
+	Hs
		948953 CD81_HUMAN (4-217): 9.18e-49: 161: 40.69		FPRP_HUMAN (37-604): 5.77e-51: 191: 19.90
+	Hs
		967365 TSN5_HUMAN (8-218): 2.45e-48: 161: 23.44		FPRP_HUMAN (37-604): 5.77e-51: 191: 19.90
+	Hs
		477478 CD63_HUMAN (3-221): 1.99e-47: 157: 18.60		FPRP_HUMAN (37-604): 5.77e-51: 191: 19.90
+	Hs
		873796 CD151_HUMAN (3-218): 9.57e-46: 153: 26.61		FPRP_HUMAN (37-604): 5.77e-51: 191: 19.90
+	Hs
		1339815 TSN14_HUMAN (12-218): 2.09e-44: 151: 22.22		FPRP_HUMAN (37-604): 5.77e-51: 191: 19.90
+	Hs
		697368 CD82_HUMAN (5-217): 6.36e-42: 144: 22.87		FPRP_HUMAN (37-604): 5.77e-51: 191: 19.90
+	Hs
		641994 CD9_HUMAN (4-221): 6.57e-52: 169: 46.02		ROBO1_HUMAN (25-507): 1.96e-32: 136: 12.83
+	Hs
		948980 CD81_HUMAN (4-217): 9.18e-49: 161: 40.69		ROBO1_HUMAN (25-507): 1.96e-32: 136: 12.83
+	Hs
		269835 CD9_HUMAN (4-221): 6.57e-52: 169: 46.02		IGSF3_HUMAN (19-305): 3.9e-20: 97.2: 17.89
+	Hs
		269850 TSN5_HUMAN (8-218): 2.45e-48: 161: 23.44		IGSF3_HUMAN (19-305): 3.9e-20: 97.2: 17.89
+	Hs
		269877 TSN14_HUMAN (12-218): 2.09e-44: 151: 22.22		IGSF3_HUMAN (19-305): 3.9e-20: 97.2: 17.89
+	Hs
		269820 TSN15_HUMAN (11-215): 2.56e-38: 135: 15.39		IGSF3_HUMAN (19-305): 3.9e-20: 97.2: 17.89
+	Hs
		1288409 TSN33_HUMAN (11-217): 2.59e-45: 153: 22.62		TITIN_HUMAN (4-593): 4.91e-11: 68.3: 8.89