HitPredict

Interactor 1: OBSL1 (O75147)
Obscurin-like protein 1
Gene: OBSL1

Interactor 2: DESP (P15924)
Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen)
Gene: DSP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24711643
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0014704 - intercalated disc
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1896 Hs			1 2871
+	Hs
		272180 OBSL1_HUMAN (1-1896): 0: 1188: 100.00		GOGB1_HUMAN (633-2516): 6.16e-51: 203: 10.49
+	Hs
		271983 OBSL1_HUMAN (1-1896): 0: 1188: 100.00		CENPF_HUMAN (607-2277): 7.13e-47: 189: 9.31
+	Hs
		272198 OBSL1_HUMAN (1-1896): 0: 1188: 100.00		PLEC_HUMAN (2198-2814): 5.42e-32: 140: 34.90
+	Hs
		272093 OBSL1_HUMAN (1-1896): 0: 1188: 100.00		DYST_HUMAN (54-1782): 2.85e-19: 98.8: 9.30
+	Hs
		272023 OBSL1_HUMAN (1-1896): 0: 1188: 100.00		EPIPL_HUMAN (2625-2847): 9.98e-13: 76.9: 18.52
+	Hs
		272551 OBSL1_HUMAN (1-1896): 0: 1188: 100.00		MACF1_HUMAN (2583-2820): 1.08e-10: 70.3: 19.25
+	Hs
		587751 TITIN_HUMAN (11-210): 2.79e-11: 71.6: 17.91		DESP_HUMAN (1-2871): 0: 839: 100.00
+	Hs
		249139 DSCAM_HUMAN (1258-1895): 1.45e-72: 272: 16.59		PLEC_HUMAN (2198-2814): 5.42e-32: 140: 34.90
+	Hs
		249122 DSCAM_HUMAN (1258-1895): 1.45e-72: 272: 16.59		DYST_HUMAN (54-1782): 2.85e-19: 98.8: 9.30
+	Mm
		267098 MYPC3_MOUSE (1-890): 5.94e-66: 248: 15.56		MYH6_MOUSE (1599-2505): 1.33e-25: 119: 11.34
+	Mm
		1037833 Q3UIK0_MOUSE (3-1082): 1.35e-64: 244: 14.65		MYH6_MOUSE (1599-2505): 1.33e-25: 119: 11.34
+	Hs
		249214 DSCAM_HUMAN (1258-1895): 1.45e-72: 272: 16.59		MACF1_HUMAN (2583-2820): 1.08e-10: 70.3: 19.25
+	Hs
		249121 DSCAM_HUMAN (1258-1895): 1.45e-72: 272: 16.59		SPTB2_HUMAN (1148-2228): 6.51e-09: 64.1: 10.53
+	Mm
		267111 MYPC3_MOUSE (1-890): 5.94e-66: 248: 15.56		MACF1_MOUSE (2583-2820): 6.57e-10: 67.6: 18.83
+	Hs
		1035528 TITIN_HUMAN (11-210): 2.79e-11: 71.6: 17.91		CENPE_HUMAN (1148-2593): 3.45e-40: 167: 9.60
+	Hs
		556926 MYPC3_HUMAN (647-880): 4.69e-11: 70.5: 25.52		MYH7_HUMAN (1443-2432): 1.99e-35: 151: 11.55
+	Hs
		1143280 MXRA5_HUMAN (1-104): 3.19e-10: 67.7: 18.10		PLEC_HUMAN (2198-2814): 5.42e-32: 140: 34.90
+	Hs
		563055 MYPC2_HUMAN (1733-1894): 4.12e-09: 63.9: 25.90		MYH8_HUMAN (1555-2358): 2.84e-30: 134: 11.97
+	Dm
		55724 Q9W053_DROME (896-975): 1.31e-09: 65.8: 19.75		A1Z9J3_DROME (810-1706): 7.33e-19: 97.2: 10.62
+	Hs
		1040292 MYPC2_HUMAN (1733-1894): 4.12e-09: 63.9: 25.90		DYST_HUMAN (54-1782): 2.85e-19: 98.8: 9.30