Interactor 1: PPM1B (O75688)
Protein phosphatase 1B (EC 3.1.3.16) (Protein phosphatase 2C isoform beta) (PP2C-beta)
Gene: PPM1B

Interactor 2: PPM1A (P35813)
Protein phosphatase 1A (EC 3.1.3.16) (Protein phosphatase 2C isoform alpha) (PP2C-alpha) (Protein phosphatase IA)
Gene: PPM1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PP2C~PP2C, PP2C~PP2C_C
Common GO terms GO:0000287 - magnesium ion binding
GO:0004722 - protein serine/threonine phosphatase activity
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006470 - protein dephosphorylation
and 9 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 479
Hs

1 382
+ At
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024