Protein: KDM4B
Lysine-specific demethylase 4B (EC 1.14.11.66) (JmjC domain-containing histone demethylation protein 3B) (Jumonji domain-containing protein 2B) ([histone H3]-trimethyl-L-lysine(9) demethylase 4B)

Gene: KDM4B
Organism: Homo sapiens
Interactions: 60
UniProt ID: O94953

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006338 - chromatin remodeling
GO:0007420 - brain development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

273385

KDM4A
Lysine-specific demethylase 4A

2

15

High-throughput

0.789

High

322676

UHRF1
E3 ubiquitin-protein ligase UHRF1

1

14

High-throughput

0.691

High

322648

TCPD
T-complex protein 1 subunit delta

3

7

High-throughput

0.667

High

322672

ZN414
Zinc finger protein 414

3

2

High-throughput

0.656

High

322669

FBX22
F-box only protein 22

3

3

Small-scale

0.640

High

161385

KMT2D
Histone-lysine N-methyltransferase 2D

1

11

Small-scale

0.618

High

322668

KMT2C
Histone-lysine N-methyltransferase 2C

1

14

Small-scale

0.618

High

322673

UHRF2
E3 ubiquitin-protein ligase UHRF2

1

14

Small-scale

0.618

High

322644

TCPZ
T-complex protein 1 subunit zeta

3

10

High-throughput

0.609

High

322646

TCPG
T-complex protein 1 subunit gamma

3

10

High-throughput

0.609

High

322653

TCPB
T-complex protein 1 subunit beta

3

10

High-throughput

0.609

High

322677

TCPH
T-complex protein 1 subunit eta

3

10

High-throughput

0.609

High

322635

ESR1
Estrogen receptor

2

20

Small-scale

0.584

High

66569

CC85C
Coiled-coil domain-containing protein 85C

2

1

High-throughput

0.558

High

322638

TCPA
T-complex protein 1 subunit alpha

2

8

High-throughput

0.558

High

322645

TCPE
T-complex protein 1 subunit epsilon

2

10

High-throughput

0.558

High

322647

TCPQ
T-complex protein 1 subunit theta

2

12

High-throughput

0.558

High

322670

TCPW
T-complex protein 1 subunit zeta-2

2

13

High-throughput

0.558

High

322656

PLCB3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3

1

1

High-throughput

0.536

High

322657

HSP7E
Heat shock 70 kDa protein 14

1

4

High-throughput

0.536

High

322663

PKN2
Serine/threonine-protein kinase N2

1

1

High-throughput

0.536

High

322664

PAR14
Protein mono-ADP-ribosyltransferase PARP14

1

1

High-throughput

0.536

High

322675

WRIP1
ATPase WRNIP1

1

9

High-throughput

0.536

High

322684

CHIP
E3 ubiquitin-protein ligase CHIP

1

2

High-throughput

0.536

High

322662

CIP4
Cdc42-interacting protein 4

1

0

High-throughput

0.513

High

322674

PUS7
Pseudouridylate synthase 7 homolog

1

0

High-throughput

0.513

High

322679

RTF2
Replication termination factor 2

1

0

High-throughput

0.513

High

322682

CHRD1
Cysteine and histidine-rich domain-containing protein 1

1

0

High-throughput

0.513

High

322666

H3C
Histone H3.3C

1

20

High-throughput

0.508

High

322650

H4
Histone H4

1

6

Small-scale

0.501

High

322634

BAG2
BAG family molecular chaperone regulator 2

1

2

High-throughput

0.489

High

322667

RHG18
Rho GTPase-activating protein 18

1

3

High-throughput

0.489

High

240348

PRKN
E3 ubiquitin-protein ligase parkin

1

6

High-throughput

0.479

High

278192

NCOR1
Nuclear receptor corepressor 1

1

6

Small-scale

0.479

High

322636

ENPL
Endoplasmin

1

4

Small-scale

0.479

High

322641

HSP74
Heat shock 70 kDa protein 4

1

6

Small-scale

0.479

High

322643

COIL
Coilin

1

1

High-throughput

0.479

High

322649

WDR5
WD repeat-containing protein 5

1

4

Small-scale

0.479

High

322651

H2B1C
Histone H2B type 1-C/E/F/G/I

1

16

High-throughput

0.479

High

322652

H31
Histone H3.1

1

20

High-throughput

0.479

High

322654

H33
Histone H3.3

1

20

High-throughput

0.479

High

322655

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

3

Small-scale

0.479

High

322658

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

2

High-throughput

0.479

High

322659

NFIX
Nuclear factor 1 X-type

1

1

High-throughput

0.479

High

322660

RBBP5
Retinoblastoma-binding protein 5

1

5

Small-scale

0.479

High

322665

GFI1B
Zinc finger protein Gfi-1b

1

3

Small-scale

0.479

High

322671

ESR2
Estrogen receptor beta

1

18

High-throughput

0.479

High

322681

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

4

Small-scale

0.479

High

322683

XPO7
Exportin-7

1

5

High-throughput

0.479

High

322685

TRAF6
TNF receptor-associated factor 6

1

8

Small-scale

0.479

High

322637

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

322639

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

322640

AKT1
RAC-alpha serine/threonine-protein kinase

1

0

Small-scale

0.458

High

322642

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

322661

SF01
Splicing factor 1

1

0

High-throughput

0.438

High

322678

MED10
Mediator of RNA polymerase II transcription subunit 10

1

0

High-throughput

0.438

High

126034

AP3B1
AP-3 complex subunit beta-1

1

0

High-throughput

0.279

Low

322680

FGOP2
FGFR1 oncogene partner 2

1

0

High-throughput

0.279

Low

66858

SPDE4
Speedy protein E4

1

0

High-throughput

0.249

Low

292966

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025