HitPredict

Interactor 1: TRIM3 (O75382)
Tripartite motif-containing protein 3 (EC 2.3.2.27) (Brain-expressed RING finger protein) (RING finger protein 22) (RING finger protein 97)
Gene: TRIM3

Interactor 2: UB2G2 (P60604)
Ubiquitin-conjugating enzyme E2 G2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme G2) (Ubiquitin carrier protein G2) (Ubiquitin-protein ligase G2)
Gene: UBE2G2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	19690564
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4
Common GO terms	GO:0000209 - protein polyubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 744 Hs			1 165
+	Hs
		279076 TRIM3_HUMAN (1-744): 0: 610: 100.00		UB2D4_HUMAN (4-164): 1.27e-73: 218: 36.03
+	Hs
		279031 TRIM3_HUMAN (1-744): 0: 610: 100.00		UB2D1_HUMAN (4-164): 2.21e-72: 215: 36.03
+	Hs
		279038 TRIM3_HUMAN (1-744): 0: 610: 100.00		UB2D2_HUMAN (4-164): 2.47e-72: 215: 36.03
+	Hs
		279037 TRIM3_HUMAN (1-744): 0: 610: 100.00		UB2D3_HUMAN (4-164): 4.3e-71: 212: 34.78
+	Hs
		1420598 TRIM2_HUMAN (1-744): 0: 556: 66.67		UB2D4_HUMAN (4-164): 1.27e-73: 218: 36.03
+	Hs
		906777 TRIM2_HUMAN (1-744): 0: 556: 66.67		UB2D1_HUMAN (4-164): 2.21e-72: 215: 36.03
+	Hs
		982314 TRIM2_HUMAN (1-744): 0: 556: 66.67		UB2D2_HUMAN (4-164): 2.47e-72: 215: 36.03
+	Hs
		957193 TRIM2_HUMAN (1-744): 0: 556: 66.67		UB2D3_HUMAN (4-164): 4.3e-71: 212: 34.78
+	Hs
		970226 TRIM2_HUMAN (1-744): 0: 556: 66.67		UB2G1_HUMAN (4-164): 3.81e-68: 205: 50.00
+	Hs
		906652 TRI32_HUMAN (1-742): 2.54e-85: 285: 17.93		UB2D1_HUMAN (4-164): 2.21e-72: 215: 36.03
+	Hs
		982174 TRI32_HUMAN (1-742): 2.54e-85: 285: 17.93		UB2D2_HUMAN (4-164): 2.47e-72: 215: 36.03
+	Hs
		957068 TRI32_HUMAN (1-742): 2.54e-85: 285: 17.93		UB2D3_HUMAN (4-164): 4.3e-71: 212: 34.78
+	Hs
		623204 RO52_HUMAN (18-481): 1.63e-84: 277: 15.87		UB2D1_HUMAN (4-164): 2.21e-72: 215: 36.03
+	Hs
		623249 RO52_HUMAN (18-481): 1.63e-84: 277: 15.87		UB2D2_HUMAN (4-164): 2.47e-72: 215: 36.03
+	Hs
		623219 RO52_HUMAN (18-481): 1.63e-84: 277: 15.87		UB2D3_HUMAN (4-164): 4.3e-71: 212: 34.78
+	Hs
		623216 RO52_HUMAN (18-481): 1.63e-84: 277: 15.87		UB2G2_HUMAN (1-165): 5.28e-70: 210: 100.00
+	Hs
		906776 TRIM5_HUMAN (15-497): 1.94e-79: 264: 15.78		UB2D1_HUMAN (4-164): 2.21e-72: 215: 36.03
+	Hs
		982313 TRIM5_HUMAN (15-497): 1.94e-79: 264: 15.78		UB2D2_HUMAN (4-164): 2.47e-72: 215: 36.03
+	Hs
		957192 TRIM5_HUMAN (15-497): 1.94e-79: 264: 15.78		UB2D3_HUMAN (4-164): 4.3e-71: 212: 34.78
+	Hs
		623191 RO52_HUMAN (18-481): 1.63e-84: 277: 15.87		UB2R1_HUMAN (4-159): 1.55e-43: 145: 49.08